2VXR
Crystal Structure of the Botulinum Neurotoxin serotype G binding domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2001 |
| Chain | Residue |
| A | ASP927 |
| A | HOH3423 |
| A | SER928 |
| A | MET929 |
| A | PHE930 |
| A | ARG1041 |
| A | ARG1169 |
| A | GLU1170 |
| A | GLY1171 |
| A | HOH3283 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2002 |
| Chain | Residue |
| A | TYR996 |
| A | SER997 |
| A | ASP1000 |
| A | TYR1005 |
| A | HOH3127 |
| A | HOH3424 |
| A | HOH3425 |
| A | HOH3426 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2003 |
| Chain | Residue |
| A | ASP1017 |
| A | GLY1020 |
| A | ASN1021 |
| A | ASN1023 |
| A | GLU1073 |
| A | HOH3143 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GOL A 2004 |
| Chain | Residue |
| A | SER1194 |
| A | GLU1196 |
| A | ILE1197 |
| A | GLN1198 |
| A | THR1199 |
| A | LYS1238 |
| A | THR1239 |
| A | PHE1240 |
| A | ILE1265 |
| A | GLN1267 |
| A | HOH3360 |
| A | HOH3427 |
| A | HOH3428 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 2005 |
| Chain | Residue |
| A | LYS943 |
| A | TYR944 |
| A | ASN945 |
| A | GLU1293 |
| A | GLY1294 |
| A | TRP1295 |
| A | THR1296 |
| A | HOH3430 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 205 |
| Details | Region: {"description":"N-terminus of receptor binding domain (N-RBD)","evidences":[{"source":"PubMed","id":"20219474","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20507178","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"Host ganglioside-binding motif","evidences":[{"source":"PubMed","id":"17185412","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Ganglioside-binding site","evidences":[{"source":"PubMed","id":"17185412","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
