2VTG

Crystal Structure of Human Iba2, trigonal crystal form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003779	molecular_function	actin binding
A	0005509	molecular_function	calcium ion binding
A	0005856	cellular_component	cytoskeleton
A	0005884	cellular_component	actin filament
A	0005925	cellular_component	focal adhesion
A	0015629	cellular_component	actin cytoskeleton
A	0032587	cellular_component	ruffle membrane
A	0046872	molecular_function	metal ion binding
A	0051015	molecular_function	actin filament binding
A	0051017	biological_process	actin filament bundle assembly
A	0070062	cellular_component	extracellular exosome
A	0097178	biological_process	ruffle assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1126

Chain	Residue
A	GLU28
A	GLU43
A	HIS85
A	ACT1128

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN A 1127

Chain	Residue
A	GLU47

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT A 1128

Chain	Residue
A	ASN44
A	HIS85
A	ZN1126
A	ARG24
A	GLU28
A	ARG31
A	GLU43

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	34
Details	Domain: {"description":"EF-hand 2; degenerate","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---