Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001510 | biological_process | RNA methylation |
| A | 0006396 | biological_process | RNA processing |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008173 | molecular_function | RNA methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030488 | biological_process | tRNA methylation |
| A | 0030697 | molecular_function | tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent |
| A | 0032259 | biological_process | methylation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE SAH A 500 |
| Chain | Residue |
| A | PHE250 |
| A | ALA324 |
| A | ASP326 |
| A | ASP340 |
| A | HOH664 |
| A | HOH627 |
| A | HOH628 |
| A | HOH629 |
| A | GLN252 |
| A | TYR278 |
| A | SER279 |
| A | GLY280 |
| A | THR283 |
| A | ASP299 |
| A | SER300 |
| A | ASN301 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A1407 |
| Chain | Residue |
| A | ARG6 |
| A | ARG51 |
| A | ARG85 |
| A | LYS86 |
| A | HOH635 |
Functional Information from PROSITE/UniProt
| site_id | PS01230 |
| Number of Residues | 32 |
| Details | TRMA_1 RNA methyltransferase trmA family signature 1. DPPRaGlhprlvkrlnrekpgv...IVYvSCNpeT |
| Chain | Residue | Details |
| A | ASP340-THR371 | |
| site_id | PS01231 |
| Number of Residues | 11 |
| Details | TRMA_2 RNA methyltransferase trmA family signature 2. LDmFPHTpHVE |
| Chain | Residue | Details |
| A | LEU389-GLU399 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU01024","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10015","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1xva |
| Chain | Residue | Details |
| A | TYR222 | |
