2VRY
Mouse Neuroglobin with heme iron in the reduced ferrous state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005092 | molecular_function | GDP-dissociation inhibitor activity |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0005829 | cellular_component | cytosol |
| A | 0015671 | biological_process | oxygen transport |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071456 | biological_process | cellular response to hypoxia |
| A | 0098809 | molecular_function | nitrite reductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM A 1150 |
| Chain | Residue |
| A | LEU41 |
| A | HIS96 |
| A | VAL109 |
| A | HOH2070 |
| A | HOH2072 |
| A | HOH2073 |
| A | HOH2073 |
| A | PHE42 |
| A | TYR44 |
| A | HIS64 |
| A | LYS67 |
| A | LYS67 |
| A | VAL68 |
| A | VAL71 |
| A | TYR88 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1151 |
| Chain | Residue |
| A | SER19 |
| A | PRO20 |
| A | LEU21 |
| A | GLU22 |
| A | ARG66 |
| A | HOH2074 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1152 |
| Chain | Residue |
| A | LEU21 |
| A | GLU22 |
| A | PRO59 |
| A | LEU62 |
| A | ASP63 |
| A | ARG66 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: distal binding residue; reversible => ECO:0000255|PROSITE-ProRule:PRU00238, ECO:0000269|PubMed:15162488, ECO:0007744|PDB:1Q1F |
| Chain | Residue | Details |
| A | HIS64 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: proximal binding residue => ECO:0000255|PROSITE-ProRule:PRU00238, ECO:0000269|PubMed:15162488, ECO:0000269|PubMed:15548613, ECO:0007744|PDB:1Q1F, ECO:0007744|PDB:1W92 |
| Chain | Residue | Details |
| A | HIS96 |
