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2VRE

crystal structure of human peroxisomal delta3,5,delta2,4-dienoyl coa isomerase

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0016853molecular_functionisomerase activity
B0003824molecular_functioncatalytic activity
B0016853molecular_functionisomerase activity
C0003824molecular_functioncatalytic activity
C0016853molecular_functionisomerase activity
Functional Information from PDB Data
site_idAC1
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CL A1290
ChainResidue
BASN192

site_idAC2
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CL B1283
ChainResidue
BASP179

site_idAC3
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CL C1284
ChainResidue
CASN192

Functional Information from PROSITE/UniProt
site_idPS00166
Number of Residues21
DetailsENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. IAaVHGgciGGGvdlvTaCDI
ChainResidueDetails
AILE138-ILE158

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P42126
ChainResidueDetails
AALA90
AGLY148
BALA90
BGLY148
CALA90
CGLY148

site_idSWS_FT_FI2
Number of Residues3
DetailsSITE: Important for catalytic activity => ECO:0000250|UniProtKB:P42126
ChainResidueDetails
AGLU171
BGLU171
CGLU171

site_idSWS_FT_FI3
Number of Residues3
DetailsSITE: Important for catalytic activity => ECO:0000250|UniProtKB:Q62651
ChainResidueDetails
AASP179
BASP179
CASP179

site_idSWS_FT_FI4
Number of Residues3
DetailsMOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:O35459
ChainResidueDetails
ALYS205
BLYS205
CLYS205

site_idSWS_FT_FI5
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569
ChainResidueDetails
ASER242
BSER242
CSER242

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1dci
ChainResidueDetails
AASP179
AGLU171

site_idCSA2
Number of Residues2
DetailsAnnotated By Reference To The Literature 1dci
ChainResidueDetails
BASP179
BGLU171

site_idCSA3
Number of Residues2
DetailsAnnotated By Reference To The Literature 1dci
ChainResidueDetails
CASP179
CGLU171

site_idCSA4
Number of Residues3
DetailsAnnotated By Reference To The Literature 1dci
ChainResidueDetails
AGLY148
AASP151
AGLU171

site_idCSA5
Number of Residues3
DetailsAnnotated By Reference To The Literature 1dci
ChainResidueDetails
BGLY148
BASP151
BGLU171

site_idCSA6
Number of Residues3
DetailsAnnotated By Reference To The Literature 1dci
ChainResidueDetails
CGLY148
CASP151
CGLU171

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PDB entries from 2024-10-30

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