2VQR

Crystal structure of a phosphonate monoester hydrolase from rhizobium leguminosarum: a new member of the alkaline phosphatase superfamily

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008484	molecular_function	sulfuric ester hydrolase activity
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 1515

Chain	Residue
A	ASP12
A	DDZ57
A	ASP324
A	HIS325

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 1516

Chain	Residue
A	ASP12
A	DDZ57
A	ASP324
A	HIS325

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 1518

Chain	Residue
A	HOH2042
A	HOH2151
A	HOH2271
A	HOH2588
A	HOH2596
A	HOH2035

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 1517

Chain	Residue
A	ARG444
A	TYR445
A	ASP459
A	ARG461
A	HOH2255

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT A 1519

Chain	Residue
A	TYR105
A	THR106
A	THR107
A	GLY126
A	ASP127
A	LEU128
A	HOH2169

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:18793651

Chain	Residue	Details
A	CYS57

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:18793651, ECO:0007744|PDB:2VQR

Chain	Residue	Details
A	ASP12
A	ASP324
A	HIS325

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: via 3-oxoalanine => ECO:0000269|PubMed:18793651

Chain	Residue	Details
A	CYS57

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: 3-oxoalanine (Cys) => ECO:0000255|PIRSR:PIRSR600917-51, ECO:0000269|PubMed:18793651

Chain	Residue	Details
A	CYS57

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