Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2VPX

Polysulfide reductase with bound quinone (UQ1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0043546	molecular_function	molybdopterin cofactor binding
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0009055	molecular_function	electron transfer activity
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E	0016491	molecular_function	oxidoreductase activity
E	0043546	molecular_function	molybdopterin cofactor binding
E	0046872	molecular_function	metal ion binding
E	0051536	molecular_function	iron-sulfur cluster binding
E	0051539	molecular_function	4 iron, 4 sulfur cluster binding
F	0009055	molecular_function	electron transfer activity
F	0046872	molecular_function	metal ion binding
F	0051536	molecular_function	iron-sulfur cluster binding
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SF4 A1764

Chain	Residue
A	CYS44
A	ASN216
A	GLY46
A	CYS47
A	TRP49
A	ARG50
A	CYS51
A	CYS79
A	ARG81
A	GLY82

site_id	AC2
Number of Residues	32
Details	BINDING SITE FOR RESIDUE MGD A1765

Chain	Residue
A	PHE48
A	HIS145
A	LEU172
A	CYS173
A	HIS333
A	TYR438
A	GLY439
A	ILE440
A	ASN441
A	HIS444
A	SER445
A	ILE465
A	ASP466
A	GLN470
A	HIS472
A	GLU482
A	ARG488
A	TYR623
A	ARG625
A	PHE631
A	ALA632
A	ARG633
A	HIS697
A	ASP716
A	ASN717
A	GLN720
A	LEU734
A	MGD1766
A	MO1767
A	HOH2009
A	HOH2384
A	HOH2386

site_id	AC3
Number of Residues	33
Details	BINDING SITE FOR RESIDUE MGD A1766

Chain	Residue
A	ARG81
A	CYS173
A	ILE206
A	GLY207
A	HIS208
A	HIS209
A	GLU212
A	ASP213
A	THR214
A	HIS215
A	VAL235
A	ASP236
A	PRO237
A	ARG238
A	PRO254
A	GLY255
A	ASP257
A	THR331
A	ARG332
A	HIS333
A	TRP336
A	TYR337
A	LEU622
A	ARG625
A	SER626
A	HIS629
A	THR630
A	PHE631
A	ARG735
A	MGD1765
A	MO1767
A	HOH2114
A	HOH2115

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MO A1767

Chain	Residue
A	CYS173
A	MGD1765
A	MGD1766

site_id	AC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SF4 B1194

Chain	Residue
B	CYS13
B	VAL14
B	CYS16
B	ALA18
B	CYS19
B	ILE38
B	CYS135
B	THR137
B	CYS139
B	ARG140

site_id	AC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE SF4 B1195

Chain	Residue
B	CYS131
B	CYS23
B	ASN27
B	ASN35
B	LEU36
B	GLN57
B	CYS116
B	THR117
B	PHE118
B	CYS119
B	PRO129
B	ALA130

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SF4 B1196

Chain	Residue
B	CYS58
B	LEU59
B	HIS60
B	CYS61
B	PRO64
B	CYS66
B	VAL83
B	CYS100
B	ALA104
B	ARG105
B	LYS115

site_id	AC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SF4 B1197

Chain	Residue
B	CYS70
B	PRO71
B	CYS90
B	ILE91
B	ALA92
B	CYS93
B	GLY94
B	ALA95
B	CYS96
B	VAL113

site_id	AC9
Number of Residues	11
Details	BINDING SITE FOR RESIDUE UQ1 C1252

Chain	Residue
B	CYS93
B	HOH2078
C	ASN18
C	HIS21
C	LEU61
C	LEU64
C	GLU67
C	HIS76
C	LEU79
C	ILE89
C	TYR130

site_id	BC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SF4 E1764

Chain	Residue
E	CYS44
E	CYS47
E	TRP49
E	ARG50
E	CYS51
E	CYS79
E	ARG81
E	GLY82
E	ASN216

site_id	BC2
Number of Residues	33
Details	BINDING SITE FOR RESIDUE MGD E1765

Chain	Residue
E	PHE48
E	HIS145
E	PRO168
E	LEU172
E	CYS173
E	HIS333
E	TYR438
E	GLY439
E	ILE440
E	ASN441
E	HIS444
E	SER445
E	ILE465
E	ASP466
E	HIS472
E	GLU482
E	ARG488
E	TYR623
E	ARG625
E	PHE631
E	ALA632
E	ARG633
E	HIS697
E	ASP716
E	ASN717
E	GLN720
E	LEU734
E	MGD1766
E	MO1767
E	HOH2010
E	HOH2395
E	HOH2414
E	HOH2448

site_id	BC3
Number of Residues	34
Details	BINDING SITE FOR RESIDUE MGD E1766

Chain	Residue
E	ARG81
E	CYS173
E	GLY207
E	HIS208
E	HIS209
E	GLU212
E	ASP213
E	THR214
E	HIS215
E	VAL235
E	ASP236
E	PRO237
E	ARG238
E	PRO254
E	GLY255
E	ASP257
E	THR331
E	ARG332
E	HIS333
E	TRP336
E	TYR337
E	LEU622
E	ARG625
E	SER626
E	PRO627
E	HIS629
E	THR630
E	PHE631
E	ARG735
E	MGD1765
E	MO1767
E	HOH2129
E	HOH2425
E	HOH2451

site_id	BC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SF4 F1194

Chain	Residue
F	CYS13
F	VAL14
F	GLY15
F	CYS16
F	CYS19
F	ILE38
F	PRO55
F	CYS135
F	CYS139
F	ARG140

site_id	BC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SF4 F1195

Chain	Residue
F	CYS23
F	ASN27
F	LEU36
F	GLN57
F	CYS116
F	THR117
F	PHE118
F	CYS119
F	PRO129
F	ALA130
F	CYS131

site_id	BC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SF4 F1196

Chain	Residue
F	CYS58
F	LEU59
F	CYS61
F	PRO65
F	CYS66
F	VAL83
F	CYS100
F	PRO101
F	TYR102
F	ARG105

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SF4 F1197

Chain	Residue
F	CYS70
F	CYS90
F	ILE91
F	ALA92
F	CYS93
F	GLY94
F	CYS96
F	VAL113

site_id	BC8
Number of Residues	13
Details	BINDING SITE FOR RESIDUE UQ1 G1251

Chain	Residue
F	ILE91
F	CYS93
G	ASN17
G	HIS20
G	LEU60
G	LEU63
G	GLU66
G	LEU78
G	PHE79
G	ILE88
G	GLY91
G	ALA92
G	TYR129

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MO E1767

Chain	Residue
E	CYS173
E	MGD1765
E	MGD1766
E	HOH2452

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACGaCIaACP

Chain	Residue	Details
B	CYS90-PRO101

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1tmo

Chain	Residue	Details
A	SER169

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1tmo

Chain	Residue	Details
E	SER169

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1tmo

Chain	Residue	Details
A	CYS173

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1tmo

Chain	Residue	Details
E	CYS173

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)