Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2VME

Structure of the wild-type discoidin II from Dictyostelium discoideum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0007010	biological_process	cytoskeleton organization
A	0007155	biological_process	cell adhesion
A	0009617	biological_process	response to bacterium
A	0009986	cellular_component	cell surface
A	0016936	molecular_function	galactoside binding
A	0030246	molecular_function	carbohydrate binding
A	0030247	molecular_function	polysaccharide binding
A	0031012	cellular_component	extracellular matrix
A	0031160	cellular_component	spore wall
A	0031982	cellular_component	vesicle
A	0045335	cellular_component	phagocytic vesicle
A	0046871	molecular_function	N-acetylgalactosamine binding
A	0046872	molecular_function	metal ion binding
A	0070492	molecular_function	oligosaccharide binding
A	0098609	biological_process	cell-cell adhesion
A	0098636	cellular_component	protein complex involved in cell adhesion
A	0140582	biological_process	adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0007010	biological_process	cytoskeleton organization
B	0007155	biological_process	cell adhesion
B	0009617	biological_process	response to bacterium
B	0009986	cellular_component	cell surface
B	0016936	molecular_function	galactoside binding
B	0030246	molecular_function	carbohydrate binding
B	0030247	molecular_function	polysaccharide binding
B	0031012	cellular_component	extracellular matrix
B	0031160	cellular_component	spore wall
B	0031982	cellular_component	vesicle
B	0045335	cellular_component	phagocytic vesicle
B	0046871	molecular_function	N-acetylgalactosamine binding
B	0046872	molecular_function	metal ion binding
B	0070492	molecular_function	oligosaccharide binding
B	0098609	biological_process	cell-cell adhesion
B	0098636	cellular_component	protein complex involved in cell adhesion
B	0140582	biological_process	adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0007010	biological_process	cytoskeleton organization
C	0007155	biological_process	cell adhesion
C	0009617	biological_process	response to bacterium
C	0009986	cellular_component	cell surface
C	0016936	molecular_function	galactoside binding
C	0030246	molecular_function	carbohydrate binding
C	0030247	molecular_function	polysaccharide binding
C	0031012	cellular_component	extracellular matrix
C	0031160	cellular_component	spore wall
C	0031982	cellular_component	vesicle
C	0045335	cellular_component	phagocytic vesicle
C	0046871	molecular_function	N-acetylgalactosamine binding
C	0046872	molecular_function	metal ion binding
C	0070492	molecular_function	oligosaccharide binding
C	0098609	biological_process	cell-cell adhesion
C	0098636	cellular_component	protein complex involved in cell adhesion
C	0140582	biological_process	adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0007010	biological_process	cytoskeleton organization
D	0007155	biological_process	cell adhesion
D	0009617	biological_process	response to bacterium
D	0009986	cellular_component	cell surface
D	0016936	molecular_function	galactoside binding
D	0030246	molecular_function	carbohydrate binding
D	0030247	molecular_function	polysaccharide binding
D	0031012	cellular_component	extracellular matrix
D	0031160	cellular_component	spore wall
D	0031982	cellular_component	vesicle
D	0045335	cellular_component	phagocytic vesicle
D	0046871	molecular_function	N-acetylgalactosamine binding
D	0046872	molecular_function	metal ion binding
D	0070492	molecular_function	oligosaccharide binding
D	0098609	biological_process	cell-cell adhesion
D	0098636	cellular_component	protein complex involved in cell adhesion
D	0140582	biological_process	adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0007010	biological_process	cytoskeleton organization
E	0007155	biological_process	cell adhesion
E	0009617	biological_process	response to bacterium
E	0009986	cellular_component	cell surface
E	0016936	molecular_function	galactoside binding
E	0030246	molecular_function	carbohydrate binding
E	0030247	molecular_function	polysaccharide binding
E	0031012	cellular_component	extracellular matrix
E	0031160	cellular_component	spore wall
E	0031982	cellular_component	vesicle
E	0045335	cellular_component	phagocytic vesicle
E	0046871	molecular_function	N-acetylgalactosamine binding
E	0046872	molecular_function	metal ion binding
E	0070492	molecular_function	oligosaccharide binding
E	0098609	biological_process	cell-cell adhesion
E	0098636	cellular_component	protein complex involved in cell adhesion
E	0140582	biological_process	adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0007010	biological_process	cytoskeleton organization
F	0007155	biological_process	cell adhesion
F	0009617	biological_process	response to bacterium
F	0009986	cellular_component	cell surface
F	0016936	molecular_function	galactoside binding
F	0030246	molecular_function	carbohydrate binding
F	0030247	molecular_function	polysaccharide binding
F	0031012	cellular_component	extracellular matrix
F	0031160	cellular_component	spore wall
F	0031982	cellular_component	vesicle
F	0045335	cellular_component	phagocytic vesicle
F	0046871	molecular_function	N-acetylgalactosamine binding
F	0046872	molecular_function	metal ion binding
F	0070492	molecular_function	oligosaccharide binding
F	0098609	biological_process	cell-cell adhesion
F	0098636	cellular_component	protein complex involved in cell adhesion
F	0140582	biological_process	adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 500

Chain	Residue
A	ASN39
A	SER40
A	ASP47
A	HOH2023
A	HOH2024

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 501

Chain	Residue
A	ASP68
B	ASP68
C	ASP68

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 502

Chain	Residue
B	TRP219

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 503

Chain	Residue
A	ARG19
A	VAL64
A	ARG94
A	TRP102
A	ALA135
A	HIS137
C	ALA12

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	ASP209
A	TYR244
B	GLN216
B	ARG218
B	TRP238

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 500

Chain	Residue
B	ASN39
B	SER40
B	ASP47
B	HOH2021
B	HOH2022
B	HOH2025

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 503

Chain	Residue
B	ARG19
B	ARG94
B	ALA135
B	HIS137

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 504

Chain	Residue
B	ASP209
C	GLN216
C	ARG218
C	TRP238

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 506

Chain	Residue
B	TYR24
B	HIS28
B	ARG81
B	GLN86
B	HIS144
B	HOH2076

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 500

Chain	Residue
C	ASN39
C	SER40
C	ASP47
C	HOH2020
C	HOH2022

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 504

Chain	Residue
A	GLN216
A	ARG218
A	TRP238
C	ASP209
C	TYR244

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE PG4 C 505

Chain	Residue
B	SER7
B	VAL8
B	SER9
B	ALA12
B	ASN13
C	ARG94
C	ASN99
C	VAL100
C	TRP102
C	HIS137
C	HOH2110

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 506

Chain	Residue
C	HIS28
C	ARG81
C	GLN86
C	HIS144
C	HOH2064

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 500

Chain	Residue
D	ASN39
D	SER40
D	ASP47
D	HOH2016
D	HOH2017

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN D 501

Chain	Residue
D	ASP68
E	ASP68
F	ASP68

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL D 504

Chain	Residue
D	ASP209
D	TYR244
E	GLN216
E	ARG218
E	TRP238

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 506

Chain	Residue
D	TYR24
D	HIS28
D	ARG81
D	GLN86

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA E 500

Chain	Residue
E	ASN39
E	SER40
E	ASP47
E	HOH2017

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL E 504

Chain	Residue
E	PHE62
E	ARG94
E	TRP102
E	HIS137

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL E 506

Chain	Residue
E	TYR24
E	HIS28
E	ARG81
E	GLN86
E	HIS144

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL E 507

Chain	Residue
E	SER182
E	GLU220

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA F 500

Chain	Residue
F	ASN39
F	SER40
F	ASP47
F	HOH2013

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL F 503

Chain	Residue
F	PHE62
F	ARG94
F	TRP102
F	HIS137

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL F 504

Chain	Residue
D	GLN216
D	ARG218
D	TRP238
F	ASP209
F	TYR244

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL F 506

Chain	Residue
F	HIS28
F	ARG81
F	GLN86

Functional Information from PROSITE/UniProt

site_id	PS01285
Number of Residues	30
Details	FA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. SWsssvldknq......FIvAGsdsvkhFvaIsTQG

Chain	Residue	Details
A	SER51-GLY80

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	Region: {"description":"Linker"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	12
Details	Motif: {"description":"Cell attachment site","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	36
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	6
Details	Modified residue: {"description":"Phosphohistidine","evidences":[{"source":"PubMed","id":"18384150","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)