2VM8

Human CRMP-2 crystallised in the presence of Mg

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0005737	cellular_component	cytoplasm
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
C	0005737	cellular_component	cytoplasm
C	0016787	molecular_function	hydrolase activity
C	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
D	0005737	cellular_component	cytoplasm
D	0016787	molecular_function	hydrolase activity
D	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 1491

Chain	Residue
B	GLU353
B	HOH2058
B	HOH2059
B	HOH2292
B	HOH2293

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1491

Chain	Residue
A	HOH2317
A	HOH2322
A	GLN81
A	GLU353
A	HOH2061
A	HOH2062

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 1491

Chain	Residue
C	GLN81
C	THR349
C	HOH2076
C	HOH2374
C	HOH2375

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: Phosphotyrosine; by FYN => ECO:0000269|PubMed:19652227

Chain	Residue	Details
C	TYR32
D	TYR32
A	TYR32
B	TYR32

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:O08553

Chain	Residue	Details
C	LYS258
D	LYS258
A	LYS258
B	LYS258

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P47942

Chain	Residue	Details
A	SER259
B	SER259
C	SER259
D	SER259

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:O08553

Chain	Residue	Details
C	TYR431
D	TYR431
A	TYR431
B	TYR431

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O08553

Chain	Residue	Details
A	SER465
B	SER465
C	SER465
D	SER465

---