2VJN
Formyl-CoA transferase mutant variant G260A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008410 | molecular_function | CoA-transferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0033608 | molecular_function | formyl-CoA transferase activity |
| A | 0033611 | biological_process | oxalate catabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008410 | molecular_function | CoA-transferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0033608 | molecular_function | formyl-CoA transferase activity |
| B | 0033611 | biological_process | oxalate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE EPE B1429 |
| Chain | Residue |
| A | TRP272 |
| B | HOH2205 |
| B | HOH2453 |
| B | HOH2454 |
| B | HOH2455 |
| B | HOH2456 |
| B | HOH2457 |
| B | HOH2458 |
| A | GLU273 |
| A | THR274 |
| A | ASP275 |
| A | ALA276 |
| A | HOH2279 |
| A | HOH2286 |
| B | ASP157 |
| B | GLY158 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00742, ECO:0000269|PubMed:15213226 |
| Chain | Residue | Details |
| A | ASP169 | |
| B | ASP169 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS15 | |
| B | ALA260 | |
| A | LEU72 | |
| A | ASN96 | |
| A | LYS137 | |
| A | ALA260 | |
| B | HIS15 | |
| B | LEU72 | |
| B | ASN96 | |
| B | LYS137 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00742, ECO:0000269|PubMed:12839984, ECO:0000269|PubMed:15213226, ECO:0000269|PubMed:18162462 |
| Chain | Residue | Details |
| A | ARG38 | |
| A | ARG104 | |
| B | ARG38 | |
| B | ARG104 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1xvt |
| Chain | Residue | Details |
| A | ASP169 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1xvt |
| Chain | Residue | Details |
| B | ASP169 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 155 |
| Chain | Residue | Details |
| A | GLN17 | electrostatic stabiliser, hydrogen bond donor |
| A | GLU140 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP169 | covalently attached, electrofuge, electrophile, nucleofuge, nucleophile |
| A | ALA260 | electrostatic stabiliser, hydrogen bond acceptor |
| A | GLY261 | electrostatic stabiliser, hydrogen bond donor |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 155 |
| Chain | Residue | Details |
| B | GLN17 | electrostatic stabiliser, hydrogen bond donor |
| B | GLU140 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP169 | covalently attached, electrofuge, electrophile, nucleofuge, nucleophile |
| B | ALA260 | electrostatic stabiliser, hydrogen bond acceptor |
| B | GLY261 | electrostatic stabiliser, hydrogen bond donor |
