2VJD

Torpedo Californica Acetylcholinesterase In Complex With A Non Hydrolysable Substrate Analogue, 4-Oxo-N,N,N- Trimethylpentanaminium - Orthorhombic space group - Dataset C at 150K

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001507	biological_process	acetylcholine catabolic process in synaptic cleft
A	0003990	molecular_function	acetylcholinesterase activity
A	0004104	molecular_function	cholinesterase activity
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0006581	biological_process	acetylcholine catabolic process
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0019695	biological_process	choline metabolic process
A	0043083	cellular_component	synaptic cleft
A	0045202	cellular_component	synapse
A	0052689	molecular_function	carboxylic ester hydrolase activity
A	0098552	cellular_component	side of membrane
B	0001507	biological_process	acetylcholine catabolic process in synaptic cleft
B	0003990	molecular_function	acetylcholinesterase activity
B	0004104	molecular_function	cholinesterase activity
B	0005615	cellular_component	extracellular space
B	0005886	cellular_component	plasma membrane
B	0006581	biological_process	acetylcholine catabolic process
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0019695	biological_process	choline metabolic process
B	0043083	cellular_component	synaptic cleft
B	0045202	cellular_component	synapse
B	0052689	molecular_function	carboxylic ester hydrolase activity
B	0098552	cellular_component	side of membrane

Functional Information from PROSITE/UniProt

site_id	PS00122
Number of Residues	16
Details	CARBOXYLESTERASE_B_1 Carboxylesterases type-B serine active site. FGGdpktVtIfGeSAG

Chain	Residue	Details
A	PHE187-GLY202

site_id	PS00941
Number of Residues	11
Details	CARBOXYLESTERASE_B_2 Carboxylesterases type-B signature 2. EDCLYLNIWvP

Chain	Residue	Details
A	GLU92-PRO102

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Acyl-ester intermediate

site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:10368299, ECO:0000269\|PubMed:16763558

site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:10368299, ECO:0000269\|PubMed:16763558, ECO:0000269\|PubMed:1678899

site_id	SWS_FT_FI5
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:10368299