2VI6

Crystal Structure of the Nanog Homeodomain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
B	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
B	0003677	molecular_function	DNA binding
B	0006355	biological_process	regulation of DNA-templated transcription
C	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
C	0003677	molecular_function	DNA binding
C	0006355	biological_process	regulation of DNA-templated transcription
D	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
D	0003677	molecular_function	DNA binding
D	0006355	biological_process	regulation of DNA-templated transcription
E	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
E	0003677	molecular_function	DNA binding
E	0006355	biological_process	regulation of DNA-templated transcription
F	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
F	0003677	molecular_function	DNA binding
F	0006355	biological_process	regulation of DNA-templated transcription
G	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
G	0003677	molecular_function	DNA binding
G	0006355	biological_process	regulation of DNA-templated transcription
H	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
H	0003677	molecular_function	DNA binding
H	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. LSsiLnLSykQVKTWFqNqrmkcK

Chain	Residue	Details
A	LEU34-LYS57

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	472
Details	DNA_BIND: Homeobox => ECO:0000255|PROSITE-ProRule:PRU00108

Chain	Residue	Details
A	LYS1-GLN60
B	LYS1-GLN60
C	LYS1-GLN60
D	LYS1-GLN60
E	LYS1-GLN60
F	LYS1-GLN60
G	LYS1-GLN60
H	LYS1-GLN60

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