2VF7
Crystal structure of UvrA2 from Deinococcus radiodurans
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006281 | biological_process | DNA repair |
| A | 0006289 | biological_process | nucleotide-excision repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009380 | cellular_component | excinuclease repair complex |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006281 | biological_process | DNA repair |
| B | 0006289 | biological_process | nucleotide-excision repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0009380 | cellular_component | excinuclease repair complex |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004518 | molecular_function | nuclease activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006281 | biological_process | DNA repair |
| C | 0006289 | biological_process | nucleotide-excision repair |
| C | 0006974 | biological_process | DNA damage response |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0009380 | cellular_component | excinuclease repair complex |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue ADP A 901 |
| Chain | Residue |
| A | TYR370 |
| A | SER537 |
| A | THR538 |
| A | GLY810 |
| A | ARG375 |
| A | ASN511 |
| A | ASN512 |
| A | VAL531 |
| A | GLY533 |
| A | SER534 |
| A | GLY535 |
| A | LYS536 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue ADP A 902 |
| Chain | Residue |
| A | HIS24 |
| A | ASN25 |
| A | VAL44 |
| A | GLY46 |
| A | SER47 |
| A | GLY48 |
| A | LYS49 |
| A | SER50 |
| A | SER51 |
| A | ARG101 |
| A | GLN726 |
| A | GLU730 |
| A | HOH1001 |
| A | HOH1045 |
| A | HOH1063 |
| A | HOH1066 |
| A | HOH1088 |
| A | HOH1098 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 903 |
| Chain | Residue |
| A | CYS151 |
| A | CYS154 |
| A | CYS287 |
| A | CYS290 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 904 |
| Chain | Residue |
| A | CYS641 |
| A | CYS644 |
| A | CYS664 |
| A | CYS667 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residue ADP B 901 |
| Chain | Residue |
| B | TYR370 |
| B | ARG375 |
| B | ASN511 |
| B | ASN512 |
| B | VAL531 |
| B | GLY533 |
| B | SER534 |
| B | GLY535 |
| B | LYS536 |
| B | SER537 |
| B | THR538 |
| B | HOH1037 |
| B | HOH1113 |
| B | HOH1137 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for residue ADP B 902 |
| Chain | Residue |
| B | HIS24 |
| B | ASN25 |
| B | VAL44 |
| B | GLY46 |
| B | SER47 |
| B | GLY48 |
| B | LYS49 |
| B | SER50 |
| B | SER51 |
| B | ARG101 |
| B | GLN726 |
| B | GLU730 |
| B | HOH1002 |
| B | HOH1028 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 903 |
| Chain | Residue |
| B | CYS151 |
| B | CYS154 |
| B | CYS287 |
| B | CYS290 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 904 |
| Chain | Residue |
| B | CYS641 |
| B | CYS644 |
| B | CYS664 |
| B | CYS667 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue ADP C 901 |
| Chain | Residue |
| C | TYR370 |
| C | ARG375 |
| C | ASN511 |
| C | ASN512 |
| C | SER532 |
| C | GLY533 |
| C | SER534 |
| C | GLY535 |
| C | LYS536 |
| C | SER537 |
| C | THR538 |
| C | GLY810 |
| C | HOH1007 |
| C | HOH1012 |
| C | HOH1025 |
| C | HOH1040 |
| site_id | AD1 |
| Number of Residues | 18 |
| Details | binding site for residue ADP C 902 |
| Chain | Residue |
| C | SER51 |
| C | ARG101 |
| C | LEU722 |
| C | GLN726 |
| C | GLU730 |
| C | MG905 |
| C | HOH1019 |
| C | HOH1034 |
| C | HOH1116 |
| C | HIS24 |
| C | ASN25 |
| C | VAL44 |
| C | SER45 |
| C | GLY46 |
| C | SER47 |
| C | GLY48 |
| C | LYS49 |
| C | SER50 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 903 |
| Chain | Residue |
| C | CYS151 |
| C | CYS154 |
| C | CYS287 |
| C | CYS290 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 904 |
| Chain | Residue |
| C | CYS641 |
| C | CYS644 |
| C | CYS664 |
| C | CYS667 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue MG C 905 |
| Chain | Residue |
| C | ARG101 |
| C | GLU735 |
| C | ADP902 |
Functional Information from PROSITE/UniProt
| site_id | PS00211 |
| Number of Residues | 15 |
| Details | ABC_TRANSPORTER_1 ABC transporters family signature. LSPGELQRLRLATQL |
| Chain | Residue | Details |
| A | LEU380-LEU394 | |
| A | LEU731-LEU745 |
