2VF5

Glucosamine-6-phosphate synthase in complex with glucosamine-6- phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0004360	molecular_function	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
X	0005515	molecular_function	protein binding
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005975	biological_process	carbohydrate metabolic process
X	0006002	biological_process	fructose 6-phosphate metabolic process
X	0006047	biological_process	UDP-N-acetylglucosamine metabolic process
X	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
X	0006487	biological_process	protein N-linked glycosylation
X	0006541	biological_process	glutamine metabolic process
X	0008483	molecular_function	transaminase activity
X	0097367	molecular_function	carbohydrate derivative binding
X	1901135	biological_process	carbohydrate derivative metabolic process
X	1901137	biological_process	carbohydrate derivative biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile; for GATase activity => ECO:0000250

Chain	Residue	Details
X	CYS1

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: For Fru-6P isomerization activity

Chain	Residue	Details
X	LYS603

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	10
Details	M-CSA 82

Chain	Residue	Details
X	ARG26	activator, electrostatic stabiliser, hydrogen bond acceptor
X	TRP74	electrostatic stabiliser, hydrogen bond donor
X	ASN98	electrostatic stabiliser, hydrogen bond donor
X	GLY99	electrostatic stabiliser, hydrogen bond donor
X	GLU481	electrostatic stabiliser, hydrogen bond acceptor
X	LYS485	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
X	GLU488	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
X	HIS504	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
X	LYS603	covalently attached, electron pair acceptor, electron pair donor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor
X	CYS1	covalently attached, nucleofuge, nucleophile, proton acceptor, proton donor

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