2VEO
X-ray structure of Candida antarctica lipase A in its closed state.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004806 | molecular_function | triacylglycerol lipase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016298 | molecular_function | lipase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004806 | molecular_function | triacylglycerol lipase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0016298 | molecular_function | lipase activity |
| B | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IUM A 1441 |
| Chain | Residue |
| A | ASP292 |
| A | GLU298 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IUM A 1442 |
| Chain | Residue |
| A | ASP220 |
| A | GLU314 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IUM B 1441 |
| Chain | Residue |
| B | ASP292 |
| B | GLU298 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IUM B 1442 |
| Chain | Residue |
| B | ASP220 |
| B | GLU314 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1443 |
| Chain | Residue |
| A | PHE149 |
| A | SER184 |
| A | ALA218 |
| A | THR221 |
| A | PHE222 |
| A | PHE233 |
| A | GLY237 |
| A | VAL238 |
| A | ASP95 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1443 |
| Chain | Residue |
| B | ASP95 |
| B | PHE149 |
| B | SER184 |
| B | GLY185 |
| B | THR221 |
| B | PHE431 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"17631665","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"18155238","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
