2VEF

Dihydropteroate synthase from Streptococcus pneumoniae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004156	molecular_function	dihydropteroate synthase activity
A	0005829	cellular_component	cytosol
A	0009396	biological_process	folic acid-containing compound biosynthetic process
A	0042558	biological_process	pteridine-containing compound metabolic process
A	0046654	biological_process	tetrahydrofolate biosynthetic process
B	0004156	molecular_function	dihydropteroate synthase activity
B	0005829	cellular_component	cytosol
B	0009396	biological_process	folic acid-containing compound biosynthetic process
B	0042558	biological_process	pteridine-containing compound metabolic process
B	0046654	biological_process	tetrahydrofolate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 A1304

Chain	Residue
A	ALA44
A	GLU45
A	GLY46
A	THR255
A	GLU256
A	ARG290
A	HOH2266
A	HOH2302
B	ASN247

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Functional Information from PROSITE/UniProt

site_id	PS00792
Number of Residues	16
Details	DHPS_1 Dihydropteroate synthase signature 1. IcGIINvTpDSFsDgG

Chain	Residue	Details
A	ILE12-GLY27

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site_id	PS00793
Number of Residues	14
Details	DHPS_2 Dihydropteroate synthase signature 2. GAsMLDIGGesTrP

Chain	Residue	Details
A	GLY46-PRO59

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"O05701","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18321242","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18321242","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2VEG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1aj0

Chain	Residue	Details
A	ASN17
A	ARG282

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1aj0

Chain	Residue	Details
B	ASN17
B	ARG282

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