2V9X
E138D variant of Escherichia coli dCTP deaminase in complex with dUTP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006226 | biological_process | dUMP biosynthetic process |
| A | 0006229 | biological_process | dUTP biosynthetic process |
| A | 0006235 | biological_process | dTTP biosynthetic process |
| A | 0008829 | molecular_function | dCTP deaminase activity |
| A | 0009117 | biological_process | nucleotide metabolic process |
| A | 0009314 | biological_process | response to radiation |
| A | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0070207 | biological_process | protein homotrimerization |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006226 | biological_process | dUMP biosynthetic process |
| B | 0006229 | biological_process | dUTP biosynthetic process |
| B | 0006235 | biological_process | dTTP biosynthetic process |
| B | 0008829 | molecular_function | dCTP deaminase activity |
| B | 0009117 | biological_process | nucleotide metabolic process |
| B | 0009314 | biological_process | response to radiation |
| B | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0070207 | biological_process | protein homotrimerization |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0006226 | biological_process | dUMP biosynthetic process |
| C | 0006229 | biological_process | dUTP biosynthetic process |
| C | 0006235 | biological_process | dTTP biosynthetic process |
| C | 0008829 | molecular_function | dCTP deaminase activity |
| C | 0009117 | biological_process | nucleotide metabolic process |
| C | 0009314 | biological_process | response to radiation |
| C | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0032991 | cellular_component | protein-containing complex |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0070207 | biological_process | protein homotrimerization |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0006226 | biological_process | dUMP biosynthetic process |
| D | 0006229 | biological_process | dUTP biosynthetic process |
| D | 0006235 | biological_process | dTTP biosynthetic process |
| D | 0008829 | molecular_function | dCTP deaminase activity |
| D | 0009117 | biological_process | nucleotide metabolic process |
| D | 0009314 | biological_process | response to radiation |
| D | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0032991 | cellular_component | protein-containing complex |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0070207 | biological_process | protein homotrimerization |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0005829 | cellular_component | cytosol |
| E | 0006226 | biological_process | dUMP biosynthetic process |
| E | 0006229 | biological_process | dUTP biosynthetic process |
| E | 0006235 | biological_process | dTTP biosynthetic process |
| E | 0008829 | molecular_function | dCTP deaminase activity |
| E | 0009117 | biological_process | nucleotide metabolic process |
| E | 0009314 | biological_process | response to radiation |
| E | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0032991 | cellular_component | protein-containing complex |
| E | 0042802 | molecular_function | identical protein binding |
| E | 0070207 | biological_process | protein homotrimerization |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0005829 | cellular_component | cytosol |
| F | 0006226 | biological_process | dUMP biosynthetic process |
| F | 0006229 | biological_process | dUTP biosynthetic process |
| F | 0006235 | biological_process | dTTP biosynthetic process |
| F | 0008829 | molecular_function | dCTP deaminase activity |
| F | 0009117 | biological_process | nucleotide metabolic process |
| F | 0009314 | biological_process | response to radiation |
| F | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0032991 | cellular_component | protein-containing complex |
| F | 0042802 | molecular_function | identical protein binding |
| F | 0070207 | biological_process | protein homotrimerization |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0005829 | cellular_component | cytosol |
| G | 0006226 | biological_process | dUMP biosynthetic process |
| G | 0006229 | biological_process | dUTP biosynthetic process |
| G | 0006235 | biological_process | dTTP biosynthetic process |
| G | 0008829 | molecular_function | dCTP deaminase activity |
| G | 0009117 | biological_process | nucleotide metabolic process |
| G | 0009314 | biological_process | response to radiation |
| G | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0032991 | cellular_component | protein-containing complex |
| G | 0042802 | molecular_function | identical protein binding |
| G | 0070207 | biological_process | protein homotrimerization |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0005829 | cellular_component | cytosol |
| H | 0006226 | biological_process | dUMP biosynthetic process |
| H | 0006229 | biological_process | dUTP biosynthetic process |
| H | 0006235 | biological_process | dTTP biosynthetic process |
| H | 0008829 | molecular_function | dCTP deaminase activity |
| H | 0009117 | biological_process | nucleotide metabolic process |
| H | 0009314 | biological_process | response to radiation |
| H | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0032991 | cellular_component | protein-containing complex |
| H | 0042802 | molecular_function | identical protein binding |
| H | 0070207 | biological_process | protein homotrimerization |
| I | 0000166 | molecular_function | nucleotide binding |
| I | 0005829 | cellular_component | cytosol |
| I | 0006226 | biological_process | dUMP biosynthetic process |
| I | 0006229 | biological_process | dUTP biosynthetic process |
| I | 0006235 | biological_process | dTTP biosynthetic process |
| I | 0008829 | molecular_function | dCTP deaminase activity |
| I | 0009117 | biological_process | nucleotide metabolic process |
| I | 0009314 | biological_process | response to radiation |
| I | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| I | 0016787 | molecular_function | hydrolase activity |
| I | 0032991 | cellular_component | protein-containing complex |
| I | 0042802 | molecular_function | identical protein binding |
| I | 0070207 | biological_process | protein homotrimerization |
| J | 0000166 | molecular_function | nucleotide binding |
| J | 0005829 | cellular_component | cytosol |
| J | 0006226 | biological_process | dUMP biosynthetic process |
| J | 0006229 | biological_process | dUTP biosynthetic process |
| J | 0006235 | biological_process | dTTP biosynthetic process |
| J | 0008829 | molecular_function | dCTP deaminase activity |
| J | 0009117 | biological_process | nucleotide metabolic process |
| J | 0009314 | biological_process | response to radiation |
| J | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| J | 0016787 | molecular_function | hydrolase activity |
| J | 0032991 | cellular_component | protein-containing complex |
| J | 0042802 | molecular_function | identical protein binding |
| J | 0070207 | biological_process | protein homotrimerization |
| K | 0000166 | molecular_function | nucleotide binding |
| K | 0005829 | cellular_component | cytosol |
| K | 0006226 | biological_process | dUMP biosynthetic process |
| K | 0006229 | biological_process | dUTP biosynthetic process |
| K | 0006235 | biological_process | dTTP biosynthetic process |
| K | 0008829 | molecular_function | dCTP deaminase activity |
| K | 0009117 | biological_process | nucleotide metabolic process |
| K | 0009314 | biological_process | response to radiation |
| K | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| K | 0016787 | molecular_function | hydrolase activity |
| K | 0032991 | cellular_component | protein-containing complex |
| K | 0042802 | molecular_function | identical protein binding |
| K | 0070207 | biological_process | protein homotrimerization |
| L | 0000166 | molecular_function | nucleotide binding |
| L | 0005829 | cellular_component | cytosol |
| L | 0006226 | biological_process | dUMP biosynthetic process |
| L | 0006229 | biological_process | dUTP biosynthetic process |
| L | 0006235 | biological_process | dTTP biosynthetic process |
| L | 0008829 | molecular_function | dCTP deaminase activity |
| L | 0009117 | biological_process | nucleotide metabolic process |
| L | 0009314 | biological_process | response to radiation |
| L | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| L | 0016787 | molecular_function | hydrolase activity |
| L | 0032991 | cellular_component | protein-containing complex |
| L | 0042802 | molecular_function | identical protein binding |
| L | 0070207 | biological_process | protein homotrimerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE DUT A1194 |
| Chain | Residue |
| A | ALA124 |
| A | LYS178 |
| A | TYR179 |
| A | GLN182 |
| A | MG1195 |
| A | HOH2039 |
| A | HOH2044 |
| C | ARG110 |
| C | SER111 |
| C | SER112 |
| C | ARG115 |
| A | ARG126 |
| C | HOH2035 |
| C | HOH2036 |
| A | ASP128 |
| A | TRP131 |
| A | ILE135 |
| A | VAL136 |
| A | TYR171 |
| A | ARG174 |
| A | ALA177 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE DUT B1194 |
| Chain | Residue |
| A | ARG110 |
| A | SER111 |
| A | SER112 |
| A | ARG115 |
| A | HOH2023 |
| B | ALA124 |
| B | ARG126 |
| B | ASP128 |
| B | TRP131 |
| B | ILE135 |
| B | VAL136 |
| B | TYR171 |
| B | ARG174 |
| B | ALA177 |
| B | LYS178 |
| B | GLN182 |
| B | MG1195 |
| B | HOH2045 |
| B | HOH2046 |
| B | HOH2047 |
| B | HOH2048 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE DUT C1194 |
| Chain | Residue |
| B | ARG110 |
| B | SER111 |
| B | SER112 |
| B | ARG115 |
| B | HOH2009 |
| B | HOH2025 |
| B | HOH2026 |
| C | ALA124 |
| C | ARG126 |
| C | ASP128 |
| C | TRP131 |
| C | ILE135 |
| C | VAL136 |
| C | TYR171 |
| C | ARG174 |
| C | ALA177 |
| C | LYS178 |
| C | TYR179 |
| C | GLN182 |
| C | MG1195 |
| C | HOH2052 |
| C | HOH2053 |
| C | HOH2054 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE DUT J1194 |
| Chain | Residue |
| J | ALA124 |
| J | ARG126 |
| J | ASP128 |
| J | TRP131 |
| J | ILE135 |
| J | VAL136 |
| J | TYR171 |
| J | MG1195 |
| J | HOH2030 |
| J | HOH2031 |
| J | HOH2032 |
| L | ARG110 |
| L | SER111 |
| L | SER112 |
| L | HOH2002 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE DUT K1194 |
| Chain | Residue |
| K | MG1195 |
| K | HOH2022 |
| K | HOH2037 |
| J | ARG110 |
| J | SER111 |
| J | SER112 |
| J | ARG115 |
| J | HOH2010 |
| J | HOH2011 |
| J | HOH2021 |
| K | ALA124 |
| K | ARG126 |
| K | ASP128 |
| K | TRP131 |
| K | ILE135 |
| K | VAL136 |
| K | TYR171 |
| K | ARG174 |
| K | ALA177 |
| K | LYS178 |
| K | TYR179 |
| K | GLN182 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE DUT L1194 |
| Chain | Residue |
| K | ARG110 |
| K | SER111 |
| K | SER112 |
| K | ARG115 |
| K | HOH2006 |
| K | HOH2019 |
| L | ALA124 |
| L | ARG126 |
| L | ASP128 |
| L | TRP131 |
| L | ILE135 |
| L | VAL136 |
| L | TYR171 |
| L | MG1195 |
| L | HOH2017 |
| L | HOH2025 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE DUT D1194 |
| Chain | Residue |
| D | ALA124 |
| D | ARG126 |
| D | ASP128 |
| D | TRP131 |
| D | ILE135 |
| D | VAL136 |
| D | TYR171 |
| D | ARG174 |
| D | LYS178 |
| D | TYR179 |
| D | GLN182 |
| D | MG1195 |
| D | HOH2027 |
| D | HOH2035 |
| D | HOH2036 |
| F | ARG110 |
| F | SER111 |
| F | SER112 |
| F | ARG115 |
| F | HOH2019 |
| site_id | AC8 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE DUT E1194 |
| Chain | Residue |
| D | ARG110 |
| D | SER111 |
| D | SER112 |
| D | ARG115 |
| D | HOH2007 |
| D | HOH2021 |
| E | ALA124 |
| E | ARG126 |
| E | ASP128 |
| E | ILE135 |
| E | VAL136 |
| E | TYR171 |
| E | ARG174 |
| E | ALA177 |
| E | LYS178 |
| E | TYR179 |
| E | GLN182 |
| E | MG1195 |
| E | HOH2038 |
| E | HOH2039 |
| E | HOH2040 |
| site_id | AC9 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE DUT F1194 |
| Chain | Residue |
| E | ARG110 |
| E | SER111 |
| E | SER112 |
| E | ARG115 |
| E | HOH2007 |
| E | HOH2008 |
| F | ALA124 |
| F | ARG126 |
| F | ASP128 |
| F | TRP131 |
| F | ILE135 |
| F | VAL136 |
| F | TYR171 |
| F | ARG174 |
| F | ALA177 |
| F | LYS178 |
| F | TYR179 |
| F | GLN182 |
| F | MG1195 |
| F | HOH2032 |
| F | HOH2033 |
| site_id | BC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE DUT I1194 |
| Chain | Residue |
| H | ARG110 |
| H | SER111 |
| H | SER112 |
| H | ARG115 |
| H | HOH2027 |
| I | ALA124 |
| I | ARG126 |
| I | ASP128 |
| I | ILE135 |
| I | VAL136 |
| I | TYR171 |
| I | ARG174 |
| I | ALA177 |
| I | LYS178 |
| I | TYR179 |
| I | GLN182 |
| I | MG1195 |
| I | HOH2026 |
| I | HOH2040 |
| I | HOH2041 |
| site_id | BC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE DUT G1194 |
| Chain | Residue |
| G | ALA124 |
| G | ARG126 |
| G | ASP128 |
| G | TRP131 |
| G | ILE135 |
| G | VAL136 |
| G | TYR171 |
| G | ARG174 |
| G | LYS178 |
| G | TYR179 |
| G | GLN182 |
| G | MG1195 |
| G | HOH2025 |
| I | ARG110 |
| I | SER111 |
| I | SER112 |
| I | ARG115 |
| I | HOH2004 |
| I | HOH2021 |
| site_id | BC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE DUT H1194 |
| Chain | Residue |
| G | ARG110 |
| G | SER111 |
| G | SER112 |
| G | ARG115 |
| G | HOH2002 |
| G | HOH2012 |
| G | HOH2013 |
| H | ALA124 |
| H | ARG126 |
| H | ASP128 |
| H | TRP131 |
| H | ILE135 |
| H | VAL136 |
| H | TYR171 |
| H | ARG174 |
| H | ALA177 |
| H | LYS178 |
| H | TYR179 |
| H | GLN182 |
| H | MG1195 |
| H | HOH2043 |
| H | HOH2044 |
| H | HOH2045 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A1195 |
| Chain | Residue |
| A | DUT1194 |
| C | HOH2011 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B1195 |
| Chain | Residue |
| A | HOH2009 |
| B | DUT1194 |
| B | HOH2045 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG C1195 |
| Chain | Residue |
| B | HOH2009 |
| C | DUT1194 |
| C | HOH2052 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG D1195 |
| Chain | Residue |
| D | DUT1194 |
| D | HOH2035 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG E1195 |
| Chain | Residue |
| D | HOH2007 |
| E | DUT1194 |
| E | HOH2039 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG F1195 |
| Chain | Residue |
| E | HOH2007 |
| E | HOH2008 |
| F | DUT1194 |
| F | HOH2032 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG G1195 |
| Chain | Residue |
| G | DUT1194 |
| I | HOH2004 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG H1195 |
| Chain | Residue |
| G | HOH2002 |
| H | DUT1194 |
| H | HOH2044 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG I1195 |
| Chain | Residue |
| I | DUT1194 |
| I | HOH2040 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG J1195 |
| Chain | Residue |
| J | DUT1194 |
| L | HOH2002 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG K1195 |
| Chain | Residue |
| J | HOH2010 |
| J | HOH2011 |
| K | DUT1194 |
| K | HOH2037 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG L1195 |
| Chain | Residue |
| K | HOH2006 |
| L | DUT1194 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C1197 |
| Chain | Residue |
| A | ARG2 |
| A | HIS125 |
| B | ARG2 |
| B | HIS125 |
| C | ARG2 |
| C | HIS125 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 K1197 |
| Chain | Residue |
| K | LEU107 |
| K | ASP108 |
| K | HIS121 |
| K | HIS125 |
| L | THR123 |
| L | HIS125 |
| site_id | CC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 G1197 |
| Chain | Residue |
| G | ARG2 |
| G | HIS125 |
| H | ARG2 |
| H | HIS125 |
| I | ARG2 |
| I | HIS125 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D1197 |
| Chain | Residue |
| D | ARG2 |
| D | HIS125 |
| E | ARG2 |
| E | HIS125 |
| F | ARG2 |
| F | HIS125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_00146, ECO:0000305|PubMed:15539408, ECO:0000305|PubMed:17996716 |
| Chain | Residue | Details |
| C | ASP138 | |
| D | ASP138 | |
| A | ASP138 | |
| B | ASP138 | |
| E | ASP138 | |
| F | ASP138 | |
| G | ASP138 | |
| H | ASP138 | |
| I | ASP138 | |
| J | ASP138 | |
| K | ASP138 | |
| L | ASP138 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00146, ECO:0000305|PubMed:15539408, ECO:0000305|PubMed:17651436, ECO:0000305|PubMed:17996716 |
| Chain | Residue | Details |
| A | ARG110 | |
| A | VAL136 | |
| B | ARG110 | |
| B | VAL136 | |
| C | ARG110 | |
| C | VAL136 | |
| D | ARG110 | |
| D | VAL136 | |
| E | ARG110 | |
| E | VAL136 | |
| G | ARG110 | |
| G | VAL136 | |
| H | ARG110 | |
| H | VAL136 | |
| I | ARG110 | |
| I | VAL136 | |
| J | ARG110 | |
| J | VAL136 | |
| K | ARG110 | |
| K | VAL136 | |
| L | ARG110 | |
| L | VAL136 | |
| F | ARG110 | |
| F | VAL136 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:15539408, ECO:0000305|PubMed:17651436, ECO:0000305|PubMed:17996716 |
| Chain | Residue | Details |
| A | ALA124 | |
| B | ALA124 | |
| C | ALA124 | |
| D | ALA124 | |
| E | ALA124 | |
| F | ALA124 | |
| G | ALA124 | |
| H | ALA124 | |
| I | ALA124 | |
| J | ALA124 | |
| K | ALA124 | |
| L | ALA124 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:15539408, ECO:0000305|PubMed:17996716 |
| Chain | Residue | Details |
| A | TYR171 | |
| B | TYR171 | |
| C | TYR171 | |
| D | TYR171 | |
| E | TYR171 | |
| F | TYR171 | |
| G | TYR171 | |
| H | TYR171 | |
| I | TYR171 | |
| J | TYR171 | |
| K | TYR171 | |
| L | TYR171 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00146, ECO:0000305|PubMed:15539408, ECO:0000305|PubMed:17996716 |
| Chain | Residue | Details |
| A | LYS178 | |
| A | GLN182 | |
| B | LYS178 | |
| B | GLN182 | |
| C | LYS178 | |
| C | GLN182 | |
| D | LYS178 | |
| D | GLN182 | |
| E | LYS178 | |
| E | GLN182 | |
| F | LYS178 | |
| F | GLN182 | |
| G | LYS178 | |
| G | GLN182 | |
| H | LYS178 | |
| H | GLN182 | |
| I | LYS178 | |
| I | GLN182 | |
| J | LYS178 | |
| J | GLN182 | |
| K | LYS178 | |
| K | GLN182 | |
| L | LYS178 | |
| L | GLN182 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| A | SER111 | electrostatic stabiliser |
| A | ARG115 | electrostatic stabiliser |
| A | ALA124 | electrostatic stabiliser |
| A | ARG126 | steric role |
| A | ASP138 | proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| B | SER111 | electrostatic stabiliser |
| B | ARG115 | electrostatic stabiliser |
| B | ALA124 | electrostatic stabiliser |
| B | ARG126 | steric role |
| B | ASP138 | proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| C | SER111 | electrostatic stabiliser |
| C | ARG115 | electrostatic stabiliser |
| C | ALA124 | electrostatic stabiliser |
| C | ARG126 | steric role |
| C | ASP138 | proton acceptor, proton donor |
| site_id | MCSA4 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| D | SER111 | electrostatic stabiliser |
| D | ARG115 | electrostatic stabiliser |
| D | ALA124 | electrostatic stabiliser |
| D | ARG126 | steric role |
| D | ASP138 | proton acceptor, proton donor |
| site_id | MCSA5 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| E | SER111 | electrostatic stabiliser |
| E | ARG115 | electrostatic stabiliser |
| E | ALA124 | electrostatic stabiliser |
| E | ARG126 | steric role |
| E | ASP138 | proton acceptor, proton donor |
| site_id | MCSA6 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| F | SER111 | electrostatic stabiliser |
| F | ARG115 | electrostatic stabiliser |
| F | ALA124 | electrostatic stabiliser |
| F | ARG126 | steric role |
| F | ASP138 | proton acceptor, proton donor |
| site_id | MCSA7 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| G | SER111 | electrostatic stabiliser |
| G | ARG115 | electrostatic stabiliser |
| G | ALA124 | electrostatic stabiliser |
| G | ARG126 | steric role |
| G | ASP138 | proton acceptor, proton donor |
| site_id | MCSA8 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| H | SER111 | electrostatic stabiliser |
| H | ARG115 | electrostatic stabiliser |
| H | ALA124 | electrostatic stabiliser |
| H | ARG126 | steric role |
| H | ASP138 | proton acceptor, proton donor |
| site_id | MCSA9 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| I | SER111 | electrostatic stabiliser |
| I | ARG115 | electrostatic stabiliser |
| I | ALA124 | electrostatic stabiliser |
| I | ARG126 | steric role |
| I | ASP138 | proton acceptor, proton donor |
| site_id | MCSA10 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| J | SER111 | electrostatic stabiliser |
| J | ARG115 | electrostatic stabiliser |
| J | ALA124 | electrostatic stabiliser |
| J | ARG126 | steric role |
| J | ASP138 | proton acceptor, proton donor |
| site_id | MCSA11 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| K | SER111 | electrostatic stabiliser |
| K | ARG115 | electrostatic stabiliser |
| K | ALA124 | electrostatic stabiliser |
| K | ARG126 | steric role |
| K | ASP138 | proton acceptor, proton donor |
| site_id | MCSA12 |
| Number of Residues | 5 |
| Details | M-CSA 732 |
| Chain | Residue | Details |
| L | SER111 | electrostatic stabiliser |
| L | ARG115 | electrostatic stabiliser |
| L | ALA124 | electrostatic stabiliser |
| L | ARG126 | steric role |
| L | ASP138 | proton acceptor, proton donor |
