2V9I
L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT E192A- K248W-L274stop)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005996 | biological_process | monosaccharide metabolic process |
| A | 0008994 | molecular_function | rhamnulose-1-phosphate aldolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016830 | molecular_function | carbon-carbon lyase activity |
| A | 0016832 | molecular_function | aldehyde-lyase activity |
| A | 0019299 | biological_process | rhamnose metabolic process |
| A | 0019301 | biological_process | rhamnose catabolic process |
| A | 0019323 | biological_process | pentose catabolic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005996 | biological_process | monosaccharide metabolic process |
| B | 0008994 | molecular_function | rhamnulose-1-phosphate aldolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016830 | molecular_function | carbon-carbon lyase activity |
| B | 0016832 | molecular_function | aldehyde-lyase activity |
| B | 0019299 | biological_process | rhamnose metabolic process |
| B | 0019301 | biological_process | rhamnose catabolic process |
| B | 0019323 | biological_process | pentose catabolic process |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B1274 |
| Chain | Residue |
| B | TRP21 |
| B | LYS23 |
| B | GLY24 |
| B | GLU27 |
| B | ASP229 |
| B | HOH2030 |
| B | HOH2206 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A1274 |
| Chain | Residue |
| A | GLY24 |
| A | GLU27 |
| A | ASP229 |
| A | HOH2024 |
| A | HOH2204 |
| A | TRP21 |
| A | LYS23 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A1275 |
| Chain | Residue |
| A | HIS141 |
| A | HIS143 |
| A | HIS212 |
| A | HOH2205 |
| A | HOH2206 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A1276 |
| Chain | Residue |
| A | GLU200 |
| A | HIS204 |
| B | HIS46 |
| B | ASP47 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B1275 |
| Chain | Residue |
| B | HIS141 |
| B | HIS143 |
| B | HIS212 |
| B | HOH2207 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A1277 |
| Chain | Residue |
| A | HIS46 |
| A | ASP47 |
| B | GLU200 |
| B | HIS204 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:11976494, ECO:0000269|PubMed:12962479 |
| Chain | Residue | Details |
| A | GLU117 | |
| B | GLU117 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11976494, ECO:0000269|PubMed:12962479 |
| Chain | Residue | Details |
| A | HIS141 | |
| A | HIS143 | |
| A | HIS212 | |
| B | HIS141 | |
| B | HIS143 | |
| B | HIS212 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| A | GLU117 | |
| A | GLU171 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| B | GLU117 | |
| B | GLU171 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| A | VAL174 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| B | VAL174 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 645 |
| Chain | Residue | Details |
| A | GLU117 | proton acceptor, proton donor |
| A | HIS141 | metal ligand |
| A | HIS143 | metal ligand |
| A | GLU171 | proton donor |
| A | HIS212 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 645 |
| Chain | Residue | Details |
| B | GLU117 | proton acceptor, proton donor |
| B | HIS141 | metal ligand |
| B | HIS143 | metal ligand |
| B | GLU171 | proton donor |
| B | HIS212 | metal ligand |
