2V90
Crystal structure of the 3rd PDZ domain of intestine- and kidney- enriched PDZ domain IKEPP (PDZD3)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006811 | biological_process | ion transport |
| A | 0007168 | biological_process | receptor guanylyl cyclase signaling pathway |
| A | 0030251 | molecular_function | guanylate cyclase inhibitor activity |
| B | 0006811 | biological_process | ion transport |
| B | 0007168 | biological_process | receptor guanylyl cyclase signaling pathway |
| B | 0030251 | molecular_function | guanylate cyclase inhibitor activity |
| C | 0006811 | biological_process | ion transport |
| C | 0007168 | biological_process | receptor guanylyl cyclase signaling pathway |
| C | 0030251 | molecular_function | guanylate cyclase inhibitor activity |
| D | 0006811 | biological_process | ion transport |
| D | 0007168 | biological_process | receptor guanylyl cyclase signaling pathway |
| D | 0030251 | molecular_function | guanylate cyclase inhibitor activity |
| E | 0006811 | biological_process | ion transport |
| E | 0007168 | biological_process | receptor guanylyl cyclase signaling pathway |
| E | 0030251 | molecular_function | guanylate cyclase inhibitor activity |
| F | 0006811 | biological_process | ion transport |
| F | 0007168 | biological_process | receptor guanylyl cyclase signaling pathway |
| F | 0030251 | molecular_function | guanylate cyclase inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1340 |
| Chain | Residue |
| A | GLY268 |
| A | LEU269 |
| A | ASP270 |
| A | HOH2073 |
| A | HOH2074 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B1340 |
| Chain | Residue |
| B | HOH2063 |
| B | HOH2064 |
| B | GLY268 |
| B | LEU269 |
| B | ASP270 |
| B | SO41341 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B1341 |
| Chain | Residue |
| B | GLY268 |
| B | ARG296 |
| B | SO41340 |
| B | HOH2065 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 498 |
| Details | Domain: {"description":"PDZ 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q99MJ6","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
