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2V81

Native KDPGal structure

Functional Information from GO Data
ChainGOidnamespacecontents
A0008674molecular_function2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity
A0016829molecular_functionlyase activity
A0034194biological_processD-galactonate catabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:17981470
ChainResidueDetails
AGLU37

site_idSWS_FT_FI2
Number of Residues1
DetailsACT_SITE: Schiff-base intermediate with substrate => ECO:0000269|PubMed:17981470
ChainResidueDetails
ALYS126

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:17981470
ChainResidueDetails
AARG14
ATHR66

site_idSWS_FT_FI4
Number of Residues1
DetailsBINDING: covalent => ECO:0000269|PubMed:17981470
ChainResidueDetails
ALYS126

site_idSWS_FT_FI5
Number of Residues1
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AGLY156

site_idSWS_FT_FI6
Number of Residues1
DetailsBINDING:
ChainResidueDetails
AGLY176

site_idSWS_FT_FI7
Number of Residues1
DetailsSITE: Orients the nucleophilic substrate
ChainResidueDetails
AARG14

site_idSWS_FT_FI8
Number of Residues1
DetailsSITE: Plays a major role in determining the stereoselectivity
ChainResidueDetails
AVAL154

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1fq0
ChainResidueDetails
ALYS126
AGLU37

226707

PDB entries from 2024-10-30

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