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2V7U

X-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with s-adenosylmethionine and chloride ion

Functional Information from GO Data
ChainGOidnamespacecontents
A0016740molecular_functiontransferase activity
A0033846molecular_functionadenosyl-fluoride synthase activity
B0016740molecular_functiontransferase activity
B0033846molecular_functionadenosyl-fluoride synthase activity
C0016740molecular_functiontransferase activity
C0033846molecular_functionadenosyl-fluoride synthase activity
Functional Information from PDB Data
site_idAC1
Number of Residues21
DetailsBINDING SITE FOR RESIDUE SAM B1299
ChainResidue
AASP16
AHOH2007
AHOH2064
BASP210
BPHE213
BASN215
BTRP217
BPHE254
BSER269
BARG270
BARG277
AASP21
BALA279
BHOH2258
ASER23
ATRP50
ATYR77
APRO78
ATHR80
ATHR155
ACL1300

site_idAC2
Number of Residues21
DetailsBINDING SITE FOR RESIDUE SAM B1300
ChainResidue
BASP16
BASP21
BSER23
BTRP50
BTYR77
BPRO78
BTHR80
BTHR155
BCL1301
BHOH2007
BHOH2078
BHOH2259
CASP210
CPHE213
CASN215
CTRP217
CPHE254
CSER269
CARG270
CARG277
CALA279

site_idAC3
Number of Residues21
DetailsBINDING SITE FOR RESIDUE SAM A1299
ChainResidue
AASP210
APHE213
AASN215
ATRP217
APHE254
ASER269
AARG270
AARG277
AALA279
CASP16
CASP21
CSER23
CTRP50
CTYR77
CPRO78
CTHR80
CTHR155
CCL1299
CHOH2008
CHOH2083
CHOH2161

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL A1300
ChainResidue
ALEU17
APHE156
AGLY158
AHOH2064
BSAM1299

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CL B1301
ChainResidue
BPHE156
BGLY158
BSAM1300
BHOH2078

site_idAC6
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CL C1299
ChainResidue
ASAM1299
CLEU17
CPHE156
CGLY158
CHOH2083

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues24
DetailsBINDING: BINDING => ECO:0000269|PubMed:14765200, ECO:0000269|PubMed:16370017, ECO:0000269|PubMed:16604208, ECO:0000269|PubMed:17985882, ECO:0000269|Ref.4, ECO:0000269|Ref.8
ChainResidueDetails
AASP16
BASP21
BTYR77
BGLY158
BASP210
BASN215
BSER269
BARG277
CASP16
CASP21
CTYR77
AASP21
CGLY158
CASP210
CASN215
CSER269
CARG277
ATYR77
AGLY158
AASP210
AASN215
ASER269
AARG277
BASP16

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PDB entries from 2024-10-30

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