2V6K
Structure of Maleyl Pyruvate Isomerase, a bacterial glutathione-s- transferase in Zeta class, in complex with substrate analogue dicarboxyethyl glutathione
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0009056 | biological_process | catabolic process |
| A | 0009072 | biological_process | aromatic amino acid metabolic process |
| A | 0016034 | molecular_function | maleylacetoacetate isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0050077 | molecular_function | maleylpyruvate isomerase activity |
| A | 1901170 | biological_process | naphthalene catabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006559 | biological_process | L-phenylalanine catabolic process |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0009056 | biological_process | catabolic process |
| B | 0009072 | biological_process | aromatic amino acid metabolic process |
| B | 0016034 | molecular_function | maleylacetoacetate isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0050077 | molecular_function | maleylpyruvate isomerase activity |
| B | 1901170 | biological_process | naphthalene catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE TGG A1213 |
| Chain | Residue |
| A | SER9 |
| A | SER65 |
| A | PRO66 |
| A | HIS104 |
| A | ASN108 |
| A | ARG109 |
| A | ARG110 |
| A | ARG176 |
| A | HOH2010 |
| A | HOH2221 |
| A | HOH2360 |
| A | GLY10 |
| A | HOH2361 |
| A | HOH2362 |
| A | HOH2363 |
| A | HOH2364 |
| A | HOH2365 |
| B | CYS101 |
| B | ASP102 |
| B | HOH2190 |
| A | THR11 |
| A | ARG14 |
| A | LEU33 |
| A | HIS38 |
| A | LEU51 |
| A | VAL52 |
| A | GLN64 |
| site_id | AC2 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE TGG B1213 |
| Chain | Residue |
| A | CYS101 |
| A | ASP102 |
| A | HOH2216 |
| B | SER9 |
| B | GLY10 |
| B | THR11 |
| B | ARG14 |
| B | LEU33 |
| B | HIS38 |
| B | LEU51 |
| B | VAL52 |
| B | GLN64 |
| B | SER65 |
| B | PRO66 |
| B | HIS104 |
| B | ASN108 |
| B | ARG109 |
| B | ARG110 |
| B | ARG176 |
| B | HOH2011 |
| B | HOH2194 |
| B | HOH2196 |
| B | HOH2285 |
| B | HOH2343 |
| B | HOH2344 |
| B | HOH2345 |
| B | HOH2346 |
| B | HOH2347 |
| B | HOH2348 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A1214 |
| Chain | Residue |
| A | ARG175 |
| A | HOH2139 |
| A | HOH2141 |
| A | HOH2325 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B1214 |
| Chain | Residue |
| B | ARG175 |
| B | HOH2133 |
| B | HOH2284 |
| B | HOH2309 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A1215 |
| Chain | Residue |
| A | ARG109 |
| A | GLU113 |
| A | ARG116 |
| A | HOH2366 |
| A | HOH2367 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B1215 |
| Chain | Residue |
| B | ARG109 |
| B | GLU113 |
| B | ARG116 |
| B | HOH2349 |
| B | HOH2350 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:18824004 |
| Chain | Residue | Details |
| A | SER9 | |
| B | VAL52 | |
| B | GLN64 | |
| B | ASP102 | |
| B | ASN108 | |
| B | ARG176 | |
| A | HIS38 | |
| A | VAL52 | |
| A | GLN64 | |
| A | ASP102 | |
| A | ASN108 | |
| A | ARG176 | |
| B | SER9 | |
| B | HIS38 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | ASN5 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | ASN5 |
