2V4I
Structure of a novel N-acyl-enzyme intermediate of an N-terminal nucleophile (Ntn) hydrolase, OAT2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
| A | 0006526 | biological_process | arginine biosynthetic process |
| B | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
| B | 0006526 | biological_process | arginine biosynthetic process |
| C | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
| C | 0006526 | biological_process | arginine biosynthetic process |
| D | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
| D | 0006526 | biological_process | arginine biosynthetic process |
| E | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
| E | 0006526 | biological_process | arginine biosynthetic process |
| F | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
| F | 0006526 | biological_process | arginine biosynthetic process |
| G | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
| G | 0006526 | biological_process | arginine biosynthetic process |
| H | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
| H | 0006526 | biological_process | arginine biosynthetic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Nucleophile |
| Chain | Residue | Details |
| B | AYA181 | |
| D | AYA181 | |
| F | AYA181 | |
| H | AYA181 | |
| E | THR148 | |
| E | LYS170 | |
| G | THR148 | |
| G | LYS170 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21796301 |
| Chain | Residue | Details |
| B | AYA181 | |
| B | GLU260 | |
| B | ASN381 | |
| B | THR386 | |
| D | AYA181 | |
| D | GLU260 | |
| D | ASN381 | |
| D | THR386 | |
| F | AYA181 | |
| F | GLU260 | |
| F | ASN381 | |
| F | THR386 | |
| H | AYA181 | |
| H | GLU260 | |
| H | ASN381 | |
| H | THR386 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole |
| Chain | Residue | Details |
| A | GLY112 | |
| C | GLY112 | |
| E | GLY112 | |
| G | GLY112 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by autolysis |
| Chain | Residue | Details |
| A | ALA180 | |
| C | ALA180 | |
| E | ALA180 | |
| G | ALA180 |
