2V4I
Structure of a novel N-acyl-enzyme intermediate of an N-terminal nucleophile (Ntn) hydrolase, OAT2
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
A | 0006526 | biological_process | L-arginine biosynthetic process |
B | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
B | 0006526 | biological_process | L-arginine biosynthetic process |
C | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
C | 0006526 | biological_process | L-arginine biosynthetic process |
D | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
D | 0006526 | biological_process | L-arginine biosynthetic process |
E | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
E | 0006526 | biological_process | L-arginine biosynthetic process |
F | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
F | 0006526 | biological_process | L-arginine biosynthetic process |
G | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
G | 0006526 | biological_process | L-arginine biosynthetic process |
H | 0004358 | molecular_function | glutamate N-acetyltransferase activity |
H | 0006526 | biological_process | L-arginine biosynthetic process |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: Nucleophile |
Chain | Residue | Details |
B | AYA181 | |
D | AYA181 | |
F | AYA181 | |
H | AYA181 | |
E | THR148 | |
E | LYS170 | |
G | THR148 | |
G | LYS170 |
site_id | SWS_FT_FI2 |
Number of Residues | 16 |
Details | BINDING: BINDING => ECO:0000269|PubMed:21796301 |
Chain | Residue | Details |
B | AYA181 | |
F | GLU260 | |
F | ASN381 | |
F | THR386 | |
H | AYA181 | |
H | GLU260 | |
H | ASN381 | |
H | THR386 | |
B | GLU260 | |
B | ASN381 | |
B | THR386 | |
D | AYA181 | |
D | GLU260 | |
D | ASN381 | |
D | THR386 | |
F | AYA181 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | SITE: Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole |
Chain | Residue | Details |
A | GLY112 | |
C | GLY112 | |
E | GLY112 | |
G | GLY112 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | SITE: Cleavage; by autolysis |
Chain | Residue | Details |
A | ALA180 | |
C | ALA180 | |
E | ALA180 | |
G | ALA180 |