2V3K
The yeast ribosome synthesis factor Emg1 alpha beta knot fold methyltransferase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000447 | biological_process | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| A | 0000472 | biological_process | endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| A | 0000480 | biological_process | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005730 | cellular_component | nucleolus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005880 | cellular_component | nuclear microtubule |
| A | 0006364 | biological_process | rRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019843 | molecular_function | rRNA binding |
| A | 0030490 | biological_process | maturation of SSU-rRNA |
| A | 0030686 | cellular_component | 90S preribosome |
| A | 0031167 | biological_process | rRNA methylation |
| A | 0032040 | cellular_component | small-subunit processome |
| A | 0032259 | biological_process | methylation |
| A | 0034399 | cellular_component | nuclear periphery |
| A | 0042254 | biological_process | ribosome biogenesis |
| A | 0042274 | biological_process | ribosomal small subunit biogenesis |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0070037 | molecular_function | rRNA (pseudouridine) methyltransferase activity |
| A | 0070475 | biological_process | rRNA base methylation |
| A | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A1252 |
| Chain | Residue |
| A | ARG129 |
| A | PRO131 |
| A | ARG132 |
| A | THR133 |
| A | ARG136 |
| A | HOH2137 |
| A | HOH2138 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A1253 |
| Chain | Residue |
| A | THR168 |
| A | LYS177 |
| A | HOH2117 |
| A | HOH2139 |
| A | LYS135 |
| A | ARG136 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE SAM A1254 |
| Chain | Residue |
| A | LEU180 |
| A | SER181 |
| A | PHE182 |
| A | LYS195 |
| A | VAL206 |
| A | GLY207 |
| A | MSE209 |
| A | ALA210 |
| A | GLY212 |
| A | ASP214 |
| A | PHE216 |
| A | GLY226 |
| A | LEU227 |
| A | SER228 |
| A | TYR230 |
| A | LEU232 |
| A | HOH2141 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18063569","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21087996","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Interaction with substrate rRNA","evidences":[{"source":"PubMed","id":"21087996","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Stabilizes Arg-88","evidences":[{"source":"PubMed","id":"21087996","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
