2V28

Apo structure of the cold active phenylalanine hydroxylase from Colwellia psychrerythraea 34H

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0004505	molecular_function	phenylalanine 4-monooxygenase activity
A	0005506	molecular_function	iron ion binding
A	0006559	biological_process	L-phenylalanine catabolic process
A	0009072	biological_process	aromatic amino acid metabolic process
A	0016714	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
A	0019293	biological_process	tyrosine biosynthetic process, by oxidation of phenylalanine
A	0046872	molecular_function	metal ion binding
B	0004497	molecular_function	monooxygenase activity
B	0004505	molecular_function	phenylalanine 4-monooxygenase activity
B	0005506	molecular_function	iron ion binding
B	0006559	biological_process	L-phenylalanine catabolic process
B	0009072	biological_process	aromatic amino acid metabolic process
B	0016714	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
B	0019293	biological_process	tyrosine biosynthetic process, by oxidation of phenylalanine
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A1268

Chain	Residue
A	ARG212
A	HIS257
A	GLU258
A	HOH2291
A	HOH2364
A	HOH2365

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B1268

Chain	Residue
B	HOH2263
B	HOH2264
B	TYR80
B	ARG93
B	LYS99

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Functional Information from PROSITE/UniProt

site_id	PS00367
Number of Residues	12
Details	BH4_AAA_HYDROXYL_1 Biopterin-dependent aromatic amino acid hydroxylases signature. PDifHEIFGHCP

Chain	Residue	Details
A	PRO118-PRO129

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