2V28

Apo structure of the cold active phenylalanine hydroxylase from Colwellia psychrerythraea 34H

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0004505	molecular_function	phenylalanine 4-monooxygenase activity
A	0005506	molecular_function	iron ion binding
A	0006559	biological_process	L-phenylalanine catabolic process
A	0006571	biological_process	L-tyrosine biosynthetic process
A	0009072	biological_process	aromatic amino acid metabolic process
A	0016714	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
B	0004497	molecular_function	monooxygenase activity
B	0004505	molecular_function	phenylalanine 4-monooxygenase activity
B	0005506	molecular_function	iron ion binding
B	0006559	biological_process	L-phenylalanine catabolic process
B	0006571	biological_process	L-tyrosine biosynthetic process
B	0009072	biological_process	aromatic amino acid metabolic process
B	0016714	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A1268

Chain	Residue
A	ARG212
A	HIS257
A	GLU258
A	HOH2291
A	HOH2364
A	HOH2365

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B1268

Chain	Residue
B	HOH2263
B	HOH2264
B	TYR80
B	ARG93
B	LYS99

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Functional Information from PROSITE/UniProt

site_id	PS00367
Number of Residues	12
Details	BH4_AAA_HYDROXYL_1 Biopterin-dependent aromatic amino acid hydroxylases signature. PDifHEIFGHCP

Chain	Residue	Details
A	PRO118-PRO129

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