2V1O

Crystal structure of N-terminal domain of acyl-CoA thioesterase 7

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016790	molecular_function	thiolester hydrolase activity
B	0016790	molecular_function	thiolester hydrolase activity
C	0016790	molecular_function	thiolester hydrolase activity
D	0016790	molecular_function	thiolester hydrolase activity
E	0016790	molecular_function	thiolester hydrolase activity
F	0016790	molecular_function	thiolester hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	31
Details	BINDING SITE FOR RESIDUE COA A1162

Chain	Residue
A	LEU62
A	GLN155
A	LYS156
A	ARG159
A	HOH2082
A	HOH2137
A	HOH2138
A	HOH2139
A	HOH2140
A	HOH2141
A	HOH2142
A	ALA63
A	HOH2143
A	HOH2144
A	HOH2145
A	HOH2146
D	VAL29
D	ILE34
D	ASP69
D	PHE70
D	LEU71
D	SER72
A	ARG64
D	PRO73
D	HOH2064
A	SER90
A	LYS91
A	HIS92
A	VAL121
A	VAL131
A	TYR152

---

site_id	AC2
Number of Residues	28
Details	BINDING SITE FOR RESIDUE COA B1162

Chain	Residue
B	LEU62
B	ALA63
B	ARG64
B	SER90
B	LYS91
B	HIS92
B	VAL121
B	TYR152
B	GLN155
B	LYS156
B	ARG159
B	HOH2063
B	HOH2087
B	HOH2088
B	HOH2089
B	HOH2090
B	HOH2091
B	HOH2093
B	HOH2094
B	HOH2095
C	VAL29
C	ILE34
C	ASP69
C	PHE70
C	LEU71
C	SER72
C	PRO73
C	HOH2074

---

site_id	AC3
Number of Residues	31
Details	BINDING SITE FOR RESIDUE COA C1162

Chain	Residue
B	VAL29
B	ILE34
B	ASP69
B	PHE70
B	LEU71
B	SER72
B	PRO73
B	HOH2021
B	HOH2057
C	LEU62
C	ALA63
C	ARG64
C	SER90
C	LYS91
C	HIS92
C	VAL121
C	VAL131
C	TYR152
C	GLN155
C	LYS156
C	ARG159
C	HOH2138
C	HOH2139
C	HOH2140
C	HOH2141
C	HOH2142
C	HOH2143
C	HOH2144
C	HOH2145
C	HOH2146
C	HOH2149

---

site_id	AC4
Number of Residues	29
Details	BINDING SITE FOR RESIDUE COA D1162

Chain	Residue
D	ARG64
D	SER90
D	LYS91
D	HIS92
D	VAL121
D	TYR152
D	GLN155
D	LYS156
D	ARG159
D	HOH2118
D	HOH2121
D	HOH2122
D	HOH2123
D	HOH2124
D	HOH2125
D	HOH2126
D	HOH2127
D	HOH2128
D	HOH2130
D	HOH2131
A	VAL29
A	ILE34
A	ASP69
A	PHE70
A	LEU71
A	SER72
A	PRO73
D	LEU62
D	ALA63

---

site_id	AC5
Number of Residues	26
Details	BINDING SITE FOR RESIDUE COA E1162

Chain	Residue
E	LEU62
E	ALA63
E	ARG64
E	SER90
E	LYS91
E	HIS92
E	VAL121
E	TYR152
E	GLN155
E	LYS156
E	ARG159
E	HOH2067
E	HOH2110
E	HOH2112
E	HOH2113
E	HOH2114
E	HOH2116
E	HOH2117
F	VAL29
F	ILE34
F	ASP69
F	PHE70
F	LEU71
F	SER72
F	PRO73
F	HOH2023

---

site_id	AC6
Number of Residues	25
Details	BINDING SITE FOR RESIDUE COA F1162

Chain	Residue
E	VAL29
E	ILE34
E	ASP69
E	PHE70
E	LEU71
E	SER72
E	PRO73
E	HOH2016
F	LEU62
F	ALA63
F	ARG64
F	SER90
F	LYS91
F	HIS92
F	SER93
F	VAL121
F	TYR152
F	GLN155
F	LYS156
F	ARG159
F	HOH2086
F	HOH2088
F	HOH2089
F	HOH2090
F	HOH2091

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"evidences":[{"source":"PubMed","id":"17563367","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O00154","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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