Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0004602 | molecular_function | glutathione peroxidase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0047066 | molecular_function | phospholipid-hydroperoxide glutathione peroxidase activity |
| A | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1171 |
| Chain | Residue |
| A | GLY124 |
| A | THR125 |
| A | LYS131 |
| A | ARG148 |
| A | SER150 |
| A | PRO151 |
| A | HOH2209 |
| A | HOH2210 |
| A | HOH2211 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1172 |
| Chain | Residue |
| A | GLY62 |
| A | HIS123 |
| A | LEU126 |
| A | THR127 |
| A | ASN128 |
| A | LI1174 |
| A | HOH2081 |
| A | HOH2083 |
| A | HOH2212 |
| A | HOH2213 |
| A | HOH2214 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 1173 |
| Chain | Residue |
| A | ASP161 |
| A | GLU164 |
| A | HOH2215 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE LI A 1174 |
| Chain | Residue |
| A | SO41172 |
| A | HOH2214 |
Functional Information from PROSITE/UniProt
| site_id | PS00460 |
| Number of Residues | 16 |
| Details | GLUTATHIONE_PEROXID_1 Glutathione peroxidases active site. GHvCLIvNVaCkCGaT |
| Chain | Residue | Details |
| A | GLY31-THR46 | |
| site_id | PS00763 |
| Number of Residues | 8 |
| Details | GLUTATHIONE_PEROXID_2 Glutathione peroxidases signature 2. LAFPCNQF |
| Chain | Residue | Details |
| A | LEU68-PHE75 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | OCS43 | |
