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2V13

Crystal Structure of Renin with Inhibitor 7

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE C40 A1341
ChainResidue
AGLN19
AILE137
AASP226
ATHR227
AGLY228
ATYR20
AASP38
AGLY40
AARG82
ATYR83
ASER84
ATHR85
APRO118

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VVFDTGSSNVWV
ChainResidueDetails
AVAL35-VAL46
AALA223-GLY234

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:20927107
ChainResidueDetails
AASP38
AASP226

site_idSWS_FT_FI2
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:2493678
ChainResidueDetails
AASN5
AASN75

Catalytic Information from CSA
site_idCSA1
Number of Residues4
DetailsAnnotated By Reference To The Literature 1avf
ChainResidueDetails
AASP38
AASP226
ATHR39
ATHR227

site_idCSA2
Number of Residues3
DetailsAnnotated By Reference To The Literature 1avf
ChainResidueDetails
AASP38
AASP226
ASER41

site_idCSA3
Number of Residues4
DetailsAnnotated By Reference To The Literature 1avf
ChainResidueDetails
AASP38
AASP226
ATYR83
ASER41

site_idCSA4
Number of Residues1
DetailsAnnotated By Reference To The Literature 1avf
ChainResidueDetails
AASP38

site_idCSA5
Number of Residues1
DetailsAnnotated By Reference To The Literature 1avf
ChainResidueDetails
AASP226

229380

PDB entries from 2024-12-25

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