2V0S
crystal structure of a hairpin exchange variant (LR1) of the targeting LINE-1 retrotransposon endonuclease
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A1237 |
| Chain | Residue |
| A | GLU43 |
| A | GOL1240 |
| A | HOH2177 |
| A | HOH2178 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A1238 |
| Chain | Residue |
| A | HIS139 |
| A | SER20 |
| A | ALA21 |
| A | ILE22 |
| A | ASP137 |
| A | SER138 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1239 |
| Chain | Residue |
| A | GLY17 |
| A | LEU18 |
| A | ASN19 |
| A | LYS23 |
| A | HIS45 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A1240 |
| Chain | Residue |
| A | GLU43 |
| A | TYR115 |
| A | ASN118 |
| A | ASP145 |
| A | ASN147 |
| A | HIS228 |
| A | MN1237 |
| A | HOH2178 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17626046","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34554261","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2V0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N8K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ako |
| Chain | Residue | Details |
| A | ASP145 | |
| A | HIS228 | |
| A | ASN14 | |
| A | ASN147 | |
| A | ASP203 |
