2V0R
crystal structure of a hairpin exchange variant (LTx) of the targeting LINE-1 retrotransposon endonuclease
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1241 |
| Chain | Residue |
| A | ASN16 |
| A | GLY17 |
| A | LEU18 |
| A | ASN19 |
| A | HIS45 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1242 |
| Chain | Residue |
| A | HOH2023 |
| A | HIS45 |
| A | LYS71 |
| A | ALA72 |
| A | TYR115 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A1243 |
| Chain | Residue |
| A | GLU43 |
| A | TYR115 |
| A | ASN118 |
| A | ASP145 |
| A | TYR193 |
| A | HIS232 |
| A | HOH2078 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A1244 |
| Chain | Residue |
| A | PRO149 |
| A | ARG155 |
| A | HOH2045 |
| A | HOH2079 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B1240 |
| Chain | Residue |
| B | HIS45 |
| B | LYS71 |
| B | ALA72 |
| B | TYR115 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1241 |
| Chain | Residue |
| B | GLY17 |
| B | LEU18 |
| B | ASN19 |
| B | HIS45 |
| B | HOH2076 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17626046","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34554261","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2V0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7N8K","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ako |
| Chain | Residue | Details |
| A | ASP207 | |
| A | ASP145 | |
| A | ASN14 | |
| A | ASN147 | |
| A | HIS232 |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ako |
| Chain | Residue | Details |
| B | ASP207 | |
| B | ASP145 | |
| B | ASN14 | |
| B | ASN147 | |
| B | HIS232 |
