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2UZ8

The crystal structure of p18, human translation elongation factor 1 epsilon 1

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005730cellular_componentnucleolus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006412biological_processtranslation
A0008285biological_processnegative regulation of cell population proliferation
A0017101cellular_componentaminoacyl-tRNA synthetase multienzyme complex
A0043065biological_processpositive regulation of apoptotic process
A0043517biological_processpositive regulation of DNA damage response, signal transduction by p53 class mediator
A1990830biological_processcellular response to leukemia inhibitory factor
A2000774biological_processpositive regulation of cellular senescence
A2001235biological_processpositive regulation of apoptotic signaling pathway
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005730cellular_componentnucleolus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006412biological_processtranslation
B0008285biological_processnegative regulation of cell population proliferation
B0017101cellular_componentaminoacyl-tRNA synthetase multienzyme complex
B0043065biological_processpositive regulation of apoptotic process
B0043517biological_processpositive regulation of DNA damage response, signal transduction by p53 class mediator
B1990830biological_processcellular response to leukemia inhibitory factor
B2000774biological_processpositive regulation of cellular senescence
B2001235biological_processpositive regulation of apoptotic signaling pathway
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE GOL A1171
ChainResidue
ALYS136
ALEU140
APHE164
AILE165
AHOH2060
AHOH2075
AHOH2078

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE GOL B1171
ChainResidue
BILE165
BHOH2051
BHOH2073
BHOH2074
BHOH2075
BLYS136
BLEU140

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylalanine => ECO:0000269|Ref.6
ChainResidueDetails
AALA2
BALA2

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
ALYS138
BLYS138

223532

PDB entries from 2024-08-07

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