Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0006102 | biological_process | isocitrate metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0006102 | biological_process | isocitrate metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ICT A1403 |
| Chain | Residue |
| A | THR76 |
| A | MG1405 |
| A | HOH2102 |
| A | HOH2136 |
| B | LYS209 |
| B | ILE212 |
| B | ASP249 |
| A | SER93 |
| A | ASN95 |
| A | ARG99 |
| A | ARG108 |
| A | ARG131 |
| A | TYR138 |
| A | ASP272 |
| A | ALA304 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ICT A1404 |
| Chain | Residue |
| A | LEU285 |
| A | HIS305 |
| A | GLY306 |
| A | VAL308 |
| A | ASN324 |
| A | MG1406 |
| A | HOH2067 |
| A | HOH2128 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ICT B1397 |
| Chain | Residue |
| A | LYS209 |
| A | ILE212 |
| A | ASP249 |
| A | HOH2088 |
| B | THR76 |
| B | SER93 |
| B | ASN95 |
| B | ARG99 |
| B | ARG108 |
| B | ARG131 |
| B | TYR138 |
| B | ASP272 |
| B | ALA304 |
| B | MG1398 |
| B | HOH2069 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A1405 |
| Chain | Residue |
| A | ASP272 |
| A | ICT1403 |
| A | HOH2102 |
| B | ASP249 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B1398 |
| Chain | Residue |
| A | ASP249 |
| B | ASP272 |
| B | ASP276 |
| B | ICT1397 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG A1406 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A1407 |
| Chain | Residue |
| A | ASP15 |
| A | GLU16 |
| A | ARG19 |
| A | GLY44 |
| A | ILE45 |
| A | GLU46 |
| A | TYR85 |
| A | HOH2017 |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NYDGDVmSDmvAsaf.GSLAM |
| Chain | Residue | Details |
| A | ASN268-MET287 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| A | VAL154 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| B | VAL154 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| A | LYS209 | |
| A | ASP249 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| B | LYS209 | |
| B | ASP249 | |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| A | PHE144 | |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| B | PHE144 | |
