2UXI
Phloretin in complex with TtgR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0001217 | molecular_function | DNA-binding transcription repressor activity |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0032993 | cellular_component | protein-DNA complex |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0001217 | molecular_function | DNA-binding transcription repressor activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0032993 | cellular_component | protein-DNA complex |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE G50 A1211 |
| Chain | Residue |
| A | ALA74 |
| A | HOH2076 |
| A | HOH2077 |
| A | HOH2078 |
| A | SER77 |
| A | GLU78 |
| A | MET89 |
| A | LEU92 |
| A | ASN110 |
| A | CYS137 |
| A | MET167 |
| A | HOH2075 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE G50 B1211 |
| Chain | Residue |
| A | HIS115 |
| A | ARG176 |
| A | HOH2054 |
| B | LEU66 |
| B | ASN110 |
| B | ARG130 |
| B | ASP172 |
| B | G501212 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE G50 B1212 |
| Chain | Residue |
| B | ALA74 |
| B | SER77 |
| B | GLU78 |
| B | MET89 |
| B | CYS137 |
| B | ILE141 |
| B | PHE168 |
| B | VAL171 |
| B | ILE175 |
| B | G501211 |
Functional Information from PROSITE/UniProt
| site_id | PS01081 |
| Number of Residues | 32 |
| Details | HTH_TETR_1 TetR-type HTH domain signature. GVartTLadIaelagVTrGaIYwHFnNKaelV |
| Chain | Residue | Details |
| A | GLY28-VAL59 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 38 |
| Details | DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335 |
| Chain | Residue | Details |
| A | THR33-PHE52 | |
| B | THR33-PHE52 |
