2UXD
Crystal structure of an extended tRNA anticodon stem loop in complex with its cognate mRNA CGGG in the context of the Thermus thermophilus 30S subunit.
Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0003735 | molecular_function | structural constituent of ribosome |
B | 0005840 | cellular_component | ribosome |
B | 0006412 | biological_process | translation |
B | 0015935 | cellular_component | small ribosomal subunit |
B | 0019843 | molecular_function | rRNA binding |
B | 0022627 | cellular_component | cytosolic small ribosomal subunit |
B | 1990904 | cellular_component | ribonucleoprotein complex |
C | 0003676 | molecular_function | nucleic acid binding |
C | 0003723 | molecular_function | RNA binding |
C | 0003729 | molecular_function | mRNA binding |
C | 0003735 | molecular_function | structural constituent of ribosome |
C | 0005840 | cellular_component | ribosome |
C | 0006412 | biological_process | translation |
C | 0019843 | molecular_function | rRNA binding |
C | 0022627 | cellular_component | cytosolic small ribosomal subunit |
C | 1990904 | cellular_component | ribonucleoprotein complex |
D | 0003723 | molecular_function | RNA binding |
D | 0003735 | molecular_function | structural constituent of ribosome |
D | 0005840 | cellular_component | ribosome |
D | 0006412 | biological_process | translation |
D | 0015935 | cellular_component | small ribosomal subunit |
D | 0019843 | molecular_function | rRNA binding |
D | 0042274 | biological_process | ribosomal small subunit biogenesis |
D | 0046872 | molecular_function | metal ion binding |
D | 1990904 | cellular_component | ribonucleoprotein complex |
E | 0003723 | molecular_function | RNA binding |
E | 0003735 | molecular_function | structural constituent of ribosome |
E | 0005737 | cellular_component | cytoplasm |
E | 0005840 | cellular_component | ribosome |
E | 0006412 | biological_process | translation |
E | 0015935 | cellular_component | small ribosomal subunit |
E | 0019843 | molecular_function | rRNA binding |
E | 1990904 | cellular_component | ribonucleoprotein complex |
F | 0003735 | molecular_function | structural constituent of ribosome |
F | 0005737 | cellular_component | cytoplasm |
F | 0005840 | cellular_component | ribosome |
F | 0006412 | biological_process | translation |
F | 0019843 | molecular_function | rRNA binding |
F | 0070181 | molecular_function | small ribosomal subunit rRNA binding |
F | 1990904 | cellular_component | ribonucleoprotein complex |
G | 0000028 | biological_process | ribosomal small subunit assembly |
G | 0000049 | molecular_function | tRNA binding |
G | 0003723 | molecular_function | RNA binding |
G | 0003729 | molecular_function | mRNA binding |
G | 0003735 | molecular_function | structural constituent of ribosome |
G | 0005840 | cellular_component | ribosome |
G | 0006412 | biological_process | translation |
G | 0015935 | cellular_component | small ribosomal subunit |
G | 0019843 | molecular_function | rRNA binding |
G | 0022627 | cellular_component | cytosolic small ribosomal subunit |
G | 1990904 | cellular_component | ribonucleoprotein complex |
H | 0003735 | molecular_function | structural constituent of ribosome |
H | 0005737 | cellular_component | cytoplasm |
H | 0005840 | cellular_component | ribosome |
H | 0006412 | biological_process | translation |
H | 0019843 | molecular_function | rRNA binding |
H | 0022627 | cellular_component | cytosolic small ribosomal subunit |
H | 1990904 | cellular_component | ribonucleoprotein complex |
I | 0000049 | molecular_function | tRNA binding |
I | 0003723 | molecular_function | RNA binding |
I | 0003735 | molecular_function | structural constituent of ribosome |
I | 0005840 | cellular_component | ribosome |
I | 0006412 | biological_process | translation |
I | 0015935 | cellular_component | small ribosomal subunit |
I | 0019843 | molecular_function | rRNA binding |
I | 1990904 | cellular_component | ribonucleoprotein complex |
J | 0000049 | molecular_function | tRNA binding |
J | 0003723 | molecular_function | RNA binding |
J | 0003735 | molecular_function | structural constituent of ribosome |
J | 0005840 | cellular_component | ribosome |
J | 0006412 | biological_process | translation |
J | 0015935 | cellular_component | small ribosomal subunit |
J | 0019843 | molecular_function | rRNA binding |
J | 1990904 | cellular_component | ribonucleoprotein complex |
K | 0003735 | molecular_function | structural constituent of ribosome |
K | 0005840 | cellular_component | ribosome |
K | 0006412 | biological_process | translation |
K | 0019843 | molecular_function | rRNA binding |
K | 0022627 | cellular_component | cytosolic small ribosomal subunit |
K | 1990904 | cellular_component | ribonucleoprotein complex |
L | 0000049 | molecular_function | tRNA binding |
L | 0003735 | molecular_function | structural constituent of ribosome |
L | 0005840 | cellular_component | ribosome |
L | 0006412 | biological_process | translation |
L | 0015935 | cellular_component | small ribosomal subunit |
L | 0019843 | molecular_function | rRNA binding |
L | 1990904 | cellular_component | ribonucleoprotein complex |
M | 0000049 | molecular_function | tRNA binding |
M | 0003676 | molecular_function | nucleic acid binding |
M | 0003723 | molecular_function | RNA binding |
M | 0003735 | molecular_function | structural constituent of ribosome |
M | 0005829 | cellular_component | cytosol |
M | 0005840 | cellular_component | ribosome |
M | 0006412 | biological_process | translation |
M | 0015935 | cellular_component | small ribosomal subunit |
M | 0019843 | molecular_function | rRNA binding |
M | 1990904 | cellular_component | ribonucleoprotein complex |
N | 0003735 | molecular_function | structural constituent of ribosome |
N | 0005737 | cellular_component | cytoplasm |
N | 0005840 | cellular_component | ribosome |
N | 0006412 | biological_process | translation |
N | 0008270 | molecular_function | zinc ion binding |
N | 0015935 | cellular_component | small ribosomal subunit |
N | 0019843 | molecular_function | rRNA binding |
N | 0046872 | molecular_function | metal ion binding |
N | 1990904 | cellular_component | ribonucleoprotein complex |
O | 0003735 | molecular_function | structural constituent of ribosome |
O | 0005737 | cellular_component | cytoplasm |
O | 0005840 | cellular_component | ribosome |
O | 0006412 | biological_process | translation |
O | 0019843 | molecular_function | rRNA binding |
O | 0022627 | cellular_component | cytosolic small ribosomal subunit |
O | 1990904 | cellular_component | ribonucleoprotein complex |
P | 0003735 | molecular_function | structural constituent of ribosome |
P | 0005737 | cellular_component | cytoplasm |
P | 0005840 | cellular_component | ribosome |
P | 0006412 | biological_process | translation |
P | 0015935 | cellular_component | small ribosomal subunit |
P | 1990904 | cellular_component | ribonucleoprotein complex |
Q | 0003735 | molecular_function | structural constituent of ribosome |
Q | 0005840 | cellular_component | ribosome |
Q | 0006412 | biological_process | translation |
Q | 0019843 | molecular_function | rRNA binding |
Q | 0022627 | cellular_component | cytosolic small ribosomal subunit |
Q | 1990904 | cellular_component | ribonucleoprotein complex |
R | 0003735 | molecular_function | structural constituent of ribosome |
R | 0005840 | cellular_component | ribosome |
R | 0006412 | biological_process | translation |
R | 0019843 | molecular_function | rRNA binding |
R | 0070181 | molecular_function | small ribosomal subunit rRNA binding |
R | 1990904 | cellular_component | ribonucleoprotein complex |
S | 0000028 | biological_process | ribosomal small subunit assembly |
S | 0003723 | molecular_function | RNA binding |
S | 0003735 | molecular_function | structural constituent of ribosome |
S | 0005737 | cellular_component | cytoplasm |
S | 0005840 | cellular_component | ribosome |
S | 0006412 | biological_process | translation |
S | 0015935 | cellular_component | small ribosomal subunit |
S | 0019843 | molecular_function | rRNA binding |
S | 0022627 | cellular_component | cytosolic small ribosomal subunit |
S | 1990904 | cellular_component | ribonucleoprotein complex |
T | 0003723 | molecular_function | RNA binding |
T | 0003735 | molecular_function | structural constituent of ribosome |
T | 0005829 | cellular_component | cytosol |
T | 0005840 | cellular_component | ribosome |
T | 0006412 | biological_process | translation |
T | 0015935 | cellular_component | small ribosomal subunit |
T | 0019843 | molecular_function | rRNA binding |
T | 0070181 | molecular_function | small ribosomal subunit rRNA binding |
T | 1990904 | cellular_component | ribonucleoprotein complex |
V | 0005840 | cellular_component | ribosome |
V | 0019843 | molecular_function | rRNA binding |
V | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PAR A 3001 |
Chain | Residue |
A | G1405 |
A | U1406 |
A | C1407 |
A | A1408 |
A | G1491 |
A | A1492 |
A | A1493 |
A | G1494 |
A | U1495 |
site_id | AC2 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3002 |
Chain | Residue |
A | C866 |
A | G867 |
site_id | AC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3003 |
Chain | Residue |
A | A1110 |
A | C1189 |
site_id | AC4 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3004 |
Chain | Residue |
A | G126 |
site_id | AC5 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3005 |
Chain | Residue |
A | G610 |
A | C624 |
site_id | AC6 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3006 |
Chain | Residue |
A | C970 |
site_id | AC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3008 |
Chain | Residue |
A | A1360 |
A | G1361 |
site_id | AC8 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3009 |
Chain | Residue |
A | G976 |
A | C1362 |
site_id | AC9 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3010 |
Chain | Residue |
A | C1352 |
V | LYS3 |
site_id | BC1 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3011 |
Chain | Residue |
A | G944 |
A | G945 |
site_id | BC2 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3012 |
Chain | Residue |
A | G1224 |
site_id | BC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG G 3013 |
Chain | Residue |
A | U12 |
A | G21 |
A | G22 |
site_id | BC4 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3015 |
Chain | Residue |
A | A766 |
A | C812 |
site_id | BC5 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3016 |
Chain | Residue |
A | A768 |
site_id | BC6 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3018 |
Chain | Residue |
A | G800 |
site_id | BC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3019 |
Chain | Residue |
A | G576 |
A | C578 |
site_id | BC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG G 3021 |
Chain | Residue |
A | G506 |
A | C508 |
A | A509 |
A | A510 |
site_id | BC9 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3022 |
Chain | Residue |
A | U560 |
A | C562 |
site_id | CC1 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3023 |
Chain | Residue |
A | U14 |
site_id | CC2 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3024 |
Chain | Residue |
A | G21 |
site_id | CC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3025 |
Chain | Residue |
A | G858 |
A | G869 |
site_id | CC4 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3027 |
Chain | Residue |
A | A937 |
site_id | CC5 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3028 |
Chain | Residue |
A | C934 |
site_id | CC6 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3029 |
Chain | Residue |
A | G1370 |
A | G1371 |
site_id | CC7 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3032 |
Chain | Residue |
A | C980 |
site_id | CC8 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3033 |
Chain | Residue |
A | G324 |
site_id | CC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG G 3034 |
Chain | Residue |
A | A1067 |
A | G1068 |
A | G1094 |
A | G1387 |
site_id | DC1 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3036 |
Chain | Residue |
A | G1526 |
site_id | DC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG G 3037 |
Chain | Residue |
A | U1510 |
A | G1511 |
A | U1512 |
A | U1522 |
A | G1523 |
site_id | DC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3038 |
Chain | Residue |
A | U182 |
A | G183 |
site_id | DC4 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3039 |
Chain | Residue |
A | C352 |
site_id | DC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG G 3041 |
Chain | Residue |
A | C1303 |
A | G1304 |
V | ASP5 |
site_id | DC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG G 3045 |
Chain | Residue |
A | G409 |
A | G410 |
A | A431 |
site_id | DC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE MG G 3046 |
Chain | Residue |
A | C121 |
A | G124 |
A | U125 |
A | G126 |
A | C235 |
A | G236 |
A | C237 |
site_id | DC8 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3049 |
Chain | Residue |
A | G886 |
A | G887 |
site_id | DC9 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3050 |
Chain | Residue |
A | G581 |
A | G758 |
site_id | EC1 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3051 |
Chain | Residue |
A | C972 |
J | LYS57 |
site_id | EC2 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3054 |
Chain | Residue |
A | G627 |
site_id | EC3 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3055 |
Chain | Residue |
A | G362 |
site_id | EC4 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3056 |
Chain | Residue |
A | G731 |
site_id | EC5 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3058 |
Chain | Residue |
A | G903 |
site_id | EC6 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3060 |
Chain | Residue |
A | G168 |
site_id | EC7 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3061 |
Chain | Residue |
A | G710 |
site_id | EC8 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE MG G 3064 |
Chain | Residue |
A | C795 |
A | U1506 |
site_id | EC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG G 3065 |
Chain | Residue |
A | U788 |
A | U789 |
A | A792 |
site_id | FC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG G 3067 |
Chain | Residue |
A | G107 |
A | G324 |
A | A325 |
A | G326 |
site_id | FC2 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3068 |
Chain | Residue |
A | A572 |
site_id | FC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE MG G 3069 |
Chain | Residue |
A | U1073 |
A | G1074 |
A | U1083 |
site_id | FC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG G 3070 |
Chain | Residue |
A | C817 |
A | G818 |
A | C1527 |
A | U1528 |
site_id | FC5 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE MG G 3071 |
Chain | Residue |
A | G800 |
site_id | FC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE K G 3072 |
Chain | Residue |
A | G293 |
A | U304 |
A | G305 |
site_id | FC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE K G 3073 |
Chain | Residue |
A | G577 |
A | U813 |
site_id | FC8 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE K G 3074 |
Chain | Residue |
A | G297 |
site_id | FC9 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE K G 3075 |
Chain | Residue |
A | G688 |
A | G700 |
site_id | GC1 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE K G 3076 |
Chain | Residue |
A | G247 |
site_id | GC2 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE K G 3079 |
Chain | Residue |
A | G494 |
site_id | GC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN G 3080 |
Chain | Residue |
D | CYS9 |
D | CYS12 |
D | CYS26 |
D | CYS31 |
site_id | GC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN G 3081 |
Chain | Residue |
N | CYS24 |
N | CYS27 |
N | ARG29 |
N | CYS40 |
N | CYS43 |
Functional Information from PROSITE/UniProt
site_id | PS00052 |
Number of Residues | 27 |
Details | RIBOSOMAL_S7 Ribosomal protein S7 signature. DvLvtaFInkimrdGKKnlaarIFydA |
Chain | Residue | Details |
G | ASP20-ALA46 |
site_id | PS00053 |
Number of Residues | 18 |
Details | RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaILSTSkGVLtdreAR |
Chain | Residue | Details |
H | GLY108-ARG125 |
site_id | PS00054 |
Number of Residues | 23 |
Details | RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALqaS.GLqVksivDdTPvPHN |
Chain | Residue | Details |
K | ILE95-ASN117 |
site_id | PS00055 |
Number of Residues | 8 |
Details | RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR |
Chain | Residue | Details |
L | LYS46-ARG53 |
site_id | PS00056 |
Number of Residues | 13 |
Details | RIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIiEsRPIS |
Chain | Residue | Details |
Q | GLY54-SER66 |
site_id | PS00057 |
Number of Residues | 24 |
Details | RIBOSOMAL_S18 Ribosomal protein S18 signature. RDYrn.VevLkrFLSEt.GKIlprRR |
Chain | Residue | Details |
R | ARG32-ARG55 |
site_id | PS00063 |
Number of Residues | 16 |
Details | ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. LAKTIKraRIlGLlPF |
Chain | Residue | Details |
R | LEU66-PHE81 |
site_id | PS00323 |
Number of Residues | 25 |
Details | RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKqhvpvyItenmVGhkLGEFapT |
Chain | Residue | Details |
S | ASN53-THR77 |
site_id | PS00360 |
Number of Residues | 19 |
Details | RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGksGQidAiklGiARAL |
Chain | Residue | Details |
I | GLY67-LEU85 |
site_id | PS00361 |
Number of Residues | 16 |
Details | RIBOSOMAL_S10 Ribosomal protein S10 signature. ArrsGAqvsGPIpLPT |
Chain | Residue | Details |
J | ALA27-THR42 |
site_id | PS00362 |
Number of Residues | 31 |
Details | RIBOSOMAL_S15 Ribosomal protein S15 signature. LseHLkvhKkDhhShrgLlmMvgqrrrLlrY |
Chain | Residue | Details |
O | LEU39-TYR69 |
site_id | PS00527 |
Number of Residues | 23 |
Details | RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CvrcgrarsvyrfFGLCRiCLR |
Chain | Residue | Details |
N | ARG23-ARG45 |
site_id | PS00548 |
Number of Residues | 35 |
Details | RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewaaqGrVplHt..LranIDygfalarTtyGvlG |
Chain | Residue | Details |
C | ALA163-GLY197 |
site_id | PS00585 |
Number of Residues | 33 |
Details | RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfrFgAlvVVGDrq.GrVGlGfgkap.EVpl.AV |
Chain | Residue | Details |
E | GLY23-VAL55 |
site_id | PS00632 |
Number of Residues | 25 |
Details | RIBOSOMAL_S4 Ribosomal protein S4 signature. LEsRLdnvVYRlgfAvSrrqARqLV |
Chain | Residue | Details |
D | LEU97-VAL121 |
site_id | PS00646 |
Number of Residues | 14 |
Details | RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ |
Chain | Residue | Details |
M | ARG88-GLN101 |
site_id | PS00962 |
Number of Residues | 12 |
Details | RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VkELLEAGVHFG |
Chain | Residue | Details |
B | VAL7-GLY18 |
site_id | PS01048 |
Number of Residues | 10 |
Details | RIBOSOMAL_S6 Ribosomal protein S6 signature. GlRRLAYpIA |
Chain | Residue | Details |
F | GLY44-ALA53 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:11866529 |
Chain | Residue | Details |
D | ARG10 | |
D | ARG13 | |
D | TYR27 | |
D | ALA32 |