2UVM

Structure of PKBalpha PH domain in complex with a novel inositol headgroup surrogate, benzene 1,2,3,4-tetrakisphosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0043491	biological_process	protein kinase B signaling

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A1117

Chain	Residue
A	HIS13
A	GVF1116
A	HOH2011

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GVF A1116

Chain	Residue
A	TYR18
A	ARG23
A	ARG25
A	ASN53
A	PHE55
A	ARG69
A	ARG86
A	NA1117
A	HOH2053
A	MET1
A	SER2
A	HIS13
A	LYS14
A	GLY16
A	GLU17

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	103
Details	Domain: {"description":"PH","evidences":[{"source":"PROSITE-ProRule","id":"PRU00145","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12176338","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12964941","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"21775285","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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