2TRC

PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0001750	cellular_component	photoreceptor outer segment
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005834	cellular_component	heterotrimeric G-protein complex
B	0007165	biological_process	signal transduction
B	0007186	biological_process	G protein-coupled receptor signaling pathway
B	0007191	biological_process	adenylate cyclase-activating dopamine receptor signaling pathway
B	0007200	biological_process	phospholipase C-activating G protein-coupled receptor signaling pathway
B	0008283	biological_process	cell population proliferation
B	0016020	cellular_component	membrane
B	0030159	molecular_function	signaling receptor complex adaptor activity
B	0044877	molecular_function	protein-containing complex binding
B	0045202	cellular_component	synapse
B	0050909	biological_process	sensory perception of taste
B	0051020	molecular_function	GTPase binding
B	0060041	biological_process	retina development in camera-type eye
B	0071380	biological_process	cellular response to prostaglandin E stimulus
B	0071870	biological_process	cellular response to catecholamine stimulus
B	0097381	cellular_component	photoreceptor disc membrane
G	0005834	cellular_component	heterotrimeric G-protein complex
G	0005886	cellular_component	plasma membrane
G	0007165	biological_process	signal transduction
G	0007186	biological_process	G protein-coupled receptor signaling pathway
G	0007602	biological_process	phototransduction
G	0008104	biological_process	protein localization
G	0016020	cellular_component	membrane
G	0031681	molecular_function	G-protein beta-subunit binding
G	0042462	biological_process	eye photoreceptor cell development
G	0097381	cellular_component	photoreceptor disc membrane
P	0008277	biological_process	regulation of G protein-coupled receptor signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GD P 1

Chain	Residue
P	GLU161
P	GLU218
P	HOH234
P	HOH257

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GD P 2

Chain	Residue
G	ASP542
G	GLU546
P	GLU206
P	HOH262

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GD P 3

Chain	Residue
G	ASP542
G	GLU546
P	GLU206
P	HOH259
P	HOH271
G	ARG541

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GD B 341

Chain	Residue
B	GLN44
B	HOH397
B	HOH399

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GD P 5

Chain	Residue
P	GLU223

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Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSAsqDgKLIIWDS

Chain	Residue	Details
B	LEU70-SER84
B	ILE157-ILE171
B	LEU285-ALA299

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKA => ECO:0000250|UniProtKB:P19632

Chain	Residue	Details
P	SER73

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphohistidine => ECO:0000269|PubMed:12486123

Chain	Residue	Details
B	HIS266

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