2TMP
N-TERMINAL DOMAIN OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 (N-TIMP-2), NMR, 49 STRUCTURES
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008191 | molecular_function | metalloendopeptidase inhibitor activity |
Functional Information from PROSITE/UniProt
| site_id | PS00288 |
| Number of Residues | 13 |
| Details | TIMP Tissue inhibitors of metalloproteinases signature. CsCsPvHPQqaFC |
| Chain | Residue | Details |
| A | CYS1-CYS13 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 125 |
| Details | Domain: {"description":"NTR","evidences":[{"source":"PROSITE-ProRule","id":"PRU00295","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Region: {"description":"Involved in metalloproteinase-binding","evidences":[{"source":"PubMed","id":"24073280","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ILW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24073280","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ILW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Site: {"description":"Involved in metalloproteinase-binding","evidences":[{"source":"PubMed","id":"24073280","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ILW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
