2THI
THIAMINASE I FROM BACILLUS THIAMINOLYTICUS
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005576 | cellular_component | extracellular region |
A | 0009230 | biological_process | thiamine catabolic process |
A | 0016740 | molecular_function | transferase activity |
A | 0050332 | molecular_function | thiamine pyridinylase activity |
B | 0005576 | cellular_component | extracellular region |
B | 0009230 | biological_process | thiamine catabolic process |
B | 0016740 | molecular_function | transferase activity |
B | 0050332 | molecular_function | thiamine pyridinylase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 B 380 |
Chain | Residue |
A | ALA281 |
A | HIS282 |
A | GLU284 |
A | LEU285 |
B | HIS282 |
B | PRO283 |
B | GLU284 |
B | LEU285 |
site_id | NUC |
Number of Residues | 1 |
Details | CYS A 113 IS THE ACTIVE SITE NUCLEOPHILE. |
Chain | Residue |
A | CYS113 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Nucleophile |
Chain | Residue | Details |
A | CYS113 | |
B | CYS113 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor |
Chain | Residue | Details |
A | GLU241 | |
B | GLU241 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | a catalytic site defined by CSA, PubMed 9843405 |
Chain | Residue | Details |
A | CYS113 | |
A | GLU241 |
site_id | CSA2 |
Number of Residues | 2 |
Details | a catalytic site defined by CSA, PubMed 9843405 |
Chain | Residue | Details |
B | CYS113 | |
B | GLU241 |
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 357 |
Chain | Residue | Details |
A | CYS113 | activator, covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
A | GLU241 | activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | ASP272 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, steric role |
site_id | MCSA2 |
Number of Residues | 3 |
Details | M-CSA 357 |
Chain | Residue | Details |
B | CYS113 | activator, covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
B | GLU241 | activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
B | ASP272 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, steric role |