2RSY

Solution structure of the SH2 domain of Csk in complex with a phosphopeptide from Cbp

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005886	cellular_component	plasma membrane
B	0035556	biological_process	intracellular signal transduction
B	0045121	cellular_component	membrane raft
B	0050868	biological_process	negative regulation of T cell activation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	89
Details	Domain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by FYN and LYN","evidences":[{"source":"PubMed","id":"10801129","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10918051","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16920712","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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