2RR2

Structure of O-fucosylated epidermal growth factor-like repeat 12 of mouse Notch-1 receptor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. ClDqigeFqCiC

Chain	Residue	Details
A	CYS16-CYS27

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site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CiCmpGyeGVyC

Chain	Residue	Details
A	CYS25-CYS36

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site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. CiCmpGYegvy....C

Chain	Residue	Details
A	CYS25-CYS36

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site_id	PS01187
Number of Residues	25
Details	EGF_CA Calcium-binding EGF-like domain signature. DvNECisnp..........Cqndat..ClDqigeFqC

Chain	Residue	Details
A	ASP1-CYS25

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q07008

Chain	Residue	Details
A	ASP1
A	VAL2
A	GLU4
A	ASP18
A	GLN19

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Interaction with DLL4 => ECO:0000250|UniProtKB:Q07008

Chain	Residue	Details
A	ASP18

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: O-linked (Glc...) serine => ECO:0000269|PubMed:21757702, ECO:0000269|PubMed:28089369

Chain	Residue	Details
A	SER7

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: O-linked (Fuc...) threonine => ECO:0000269|PubMed:21757702, ECO:0000269|PubMed:28089369

Chain	Residue	Details
A	THR15

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