2ROK

Solution structure of the cap-binding domain of PARN complexed with the cap analog

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0004535	molecular_function	poly(A)-specific ribonuclease activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006402	biological_process	mRNA catabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 7MG A 523

Chain	Residue
A	PHE445
A	LYS447
A	TRP449
A	LYS450
A	THR451
A	TRP468
A	ASP470
A	ASP471

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GDP A 524

Chain	Residue
A	TRP449
A	LYS450
A	TRP468
A	ASP471
A	LYS447

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O95453

Chain	Residue	Details
A	LYS492

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