2RKJ

Cocrystal structure of a tyrosyl-tRNA synthetase splicing factor with a group I intron RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004831	molecular_function	tyrosine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006437	biological_process	tyrosyl-tRNA aminoacylation
B	0000166	molecular_function	nucleotide binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004831	molecular_function	tyrosine-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006437	biological_process	tyrosyl-tRNA aminoacylation
E	0000166	molecular_function	nucleotide binding
E	0004812	molecular_function	aminoacyl-tRNA ligase activity
E	0004831	molecular_function	tyrosine-tRNA ligase activity
E	0005524	molecular_function	ATP binding
E	0006418	biological_process	tRNA aminoacylation for protein translation
E	0006437	biological_process	tyrosyl-tRNA aminoacylation
F	0000166	molecular_function	nucleotide binding
F	0004812	molecular_function	aminoacyl-tRNA ligase activity
F	0004831	molecular_function	tyrosine-tRNA ligase activity
F	0005524	molecular_function	ATP binding
F	0006418	biological_process	tRNA aminoacylation for protein translation
F	0006437	biological_process	tyrosyl-tRNA aminoacylation
I	0000166	molecular_function	nucleotide binding
I	0004812	molecular_function	aminoacyl-tRNA ligase activity
I	0004831	molecular_function	tyrosine-tRNA ligase activity
I	0005524	molecular_function	ATP binding
I	0006418	biological_process	tRNA aminoacylation for protein translation
I	0006437	biological_process	tyrosyl-tRNA aminoacylation
J	0000166	molecular_function	nucleotide binding
J	0004812	molecular_function	aminoacyl-tRNA ligase activity
J	0004831	molecular_function	tyrosine-tRNA ligase activity
J	0005524	molecular_function	ATP binding
J	0006418	biological_process	tRNA aminoacylation for protein translation
J	0006437	biological_process	tyrosyl-tRNA aminoacylation
M	0000166	molecular_function	nucleotide binding
M	0004812	molecular_function	aminoacyl-tRNA ligase activity
M	0004831	molecular_function	tyrosine-tRNA ligase activity
M	0005524	molecular_function	ATP binding
M	0006418	biological_process	tRNA aminoacylation for protein translation
M	0006437	biological_process	tyrosyl-tRNA aminoacylation
N	0000166	molecular_function	nucleotide binding
N	0004812	molecular_function	aminoacyl-tRNA ligase activity
N	0004831	molecular_function	tyrosine-tRNA ligase activity
N	0005524	molecular_function	ATP binding
N	0006418	biological_process	tRNA aminoacylation for protein translation
N	0006437	biological_process	tyrosyl-tRNA aminoacylation

Functional Information from PROSITE/UniProt

site_id	PS00178
Number of Residues	11
Details	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. Pt.APsLHVGHL

Chain	Residue	Details
A	PRO104-LEU114

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	72
Details	Motif: {"description":"'HIGH' region"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	32
Details	Motif: {"description":"'KMSKS' region"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	56
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9Y2Z4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1d2r

Chain	Residue	Details
A	LYS324
A	LYS327

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1d2r

Chain	Residue	Details
B	LYS324
B	LYS327

---

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1d2r

Chain	Residue	Details
E	LYS324
E	LYS327

---

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1d2r

Chain	Residue	Details
F	LYS324
F	LYS327

---

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1d2r

Chain	Residue	Details
I	LYS324
I	LYS327

---

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1d2r

Chain	Residue	Details
J	LYS324
J	LYS327

---

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1d2r

Chain	Residue	Details
M	LYS324
M	LYS327

---

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1d2r

Chain	Residue	Details
N	LYS324
N	LYS327

---