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2RI4

Crystal Structure determination of Goat Methemoglobin at 2.7 Angstrom

Functional Information from GO Data
ChainGOidnamespacecontents
A0004601molecular_functionperoxidase activity
A0005344molecular_functionoxygen carrier activity
A0005506molecular_functioniron ion binding
A0005833cellular_componenthemoglobin complex
A0015671biological_processoxygen transport
A0019825molecular_functionoxygen binding
A0020037molecular_functionheme binding
A0031720molecular_functionhaptoglobin binding
A0031838cellular_componenthaptoglobin-hemoglobin complex
A0042744biological_processhydrogen peroxide catabolic process
A0043177molecular_functionorganic acid binding
A0046872molecular_functionmetal ion binding
A0072562cellular_componentblood microparticle
A0098869biological_processcellular oxidant detoxification
B0005344molecular_functionoxygen carrier activity
B0005833cellular_componenthemoglobin complex
B0015671biological_processoxygen transport
B0019825molecular_functionoxygen binding
B0020037molecular_functionheme binding
B0046872molecular_functionmetal ion binding
C0004601molecular_functionperoxidase activity
C0005344molecular_functionoxygen carrier activity
C0005506molecular_functioniron ion binding
C0005833cellular_componenthemoglobin complex
C0015671biological_processoxygen transport
C0019825molecular_functionoxygen binding
C0020037molecular_functionheme binding
C0031720molecular_functionhaptoglobin binding
C0031838cellular_componenthaptoglobin-hemoglobin complex
C0042744biological_processhydrogen peroxide catabolic process
C0043177molecular_functionorganic acid binding
C0046872molecular_functionmetal ion binding
C0072562cellular_componentblood microparticle
C0098869biological_processcellular oxidant detoxification
D0005344molecular_functionoxygen carrier activity
D0005833cellular_componenthemoglobin complex
D0015671biological_processoxygen transport
D0019825molecular_functionoxygen binding
D0020037molecular_functionheme binding
D0046872molecular_functionmetal ion binding
I0004601molecular_functionperoxidase activity
I0005344molecular_functionoxygen carrier activity
I0005506molecular_functioniron ion binding
I0005833cellular_componenthemoglobin complex
I0015671biological_processoxygen transport
I0019825molecular_functionoxygen binding
I0020037molecular_functionheme binding
I0031720molecular_functionhaptoglobin binding
I0031838cellular_componenthaptoglobin-hemoglobin complex
I0042744biological_processhydrogen peroxide catabolic process
I0043177molecular_functionorganic acid binding
I0046872molecular_functionmetal ion binding
I0072562cellular_componentblood microparticle
I0098869biological_processcellular oxidant detoxification
J0005344molecular_functionoxygen carrier activity
J0005833cellular_componenthemoglobin complex
J0015671biological_processoxygen transport
J0019825molecular_functionoxygen binding
J0020037molecular_functionheme binding
J0046872molecular_functionmetal ion binding
K0004601molecular_functionperoxidase activity
K0005344molecular_functionoxygen carrier activity
K0005506molecular_functioniron ion binding
K0005833cellular_componenthemoglobin complex
K0015671biological_processoxygen transport
K0019825molecular_functionoxygen binding
K0020037molecular_functionheme binding
K0031720molecular_functionhaptoglobin binding
K0031838cellular_componenthaptoglobin-hemoglobin complex
K0042744biological_processhydrogen peroxide catabolic process
K0043177molecular_functionorganic acid binding
K0046872molecular_functionmetal ion binding
K0072562cellular_componentblood microparticle
K0098869biological_processcellular oxidant detoxification
L0005344molecular_functionoxygen carrier activity
L0005833cellular_componenthemoglobin complex
L0015671biological_processoxygen transport
L0019825molecular_functionoxygen binding
L0020037molecular_functionheme binding
L0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE HEM A 142
ChainResidue
ATYR42
AASN97
APHE98
ALEU101
AVAL132
APHE43
AHIS58
ALYS61
AALA65
ALEU66
ALEU86
AHIS87
AVAL93

site_idAC2
Number of Residues12
DetailsBINDING SITE FOR RESIDUE HEM B 147
ChainResidue
BPHE41
BPHE42
BHIS63
BVAL67
BSER70
BLEU88
BHIS92
BLEU96
BVAL98
BASN102
BLEU141
BHOH149

site_idAC3
Number of Residues13
DetailsBINDING SITE FOR RESIDUE HEM C 142
ChainResidue
CTYR42
CPHE43
CHIS58
CLYS61
CVAL62
CLEU86
CHIS87
CLEU91
CASN97
CPHE98
CLEU101
CLEU136
CHOH145

site_idAC4
Number of Residues16
DetailsBINDING SITE FOR RESIDUE HEM D 147
ChainResidue
CSER81
DPHE41
DPHE42
DHIS63
DLYS66
DVAL67
DSER70
DPHE71
DHIS92
DLEU96
DVAL98
DASN102
DLEU106
DLEU141
DHOH149
DHOH150

site_idAC5
Number of Residues14
DetailsBINDING SITE FOR RESIDUE HEM I 142
ChainResidue
ITYR42
IPHE43
IHIS45
IHIS58
ILYS61
IVAL62
ILEU83
IHIS87
IASN97
IPHE98
ILEU101
ILEU136
IHOH145
IHOH146

site_idAC6
Number of Residues13
DetailsBINDING SITE FOR RESIDUE HEM J 147
ChainResidue
JTHR38
JPHE42
JHIS63
JLYS66
JSER70
JLEU88
JLEU91
JHIS92
JLEU96
JVAL98
JASN102
JLEU106
JHOH148

site_idAC7
Number of Residues11
DetailsBINDING SITE FOR RESIDUE HEM K 142
ChainResidue
KTYR42
KPHE43
KHIS45
KHIS58
KLYS61
KLEU66
KHIS87
KLEU91
KASN97
KPHE98
KLEU101

site_idAC8
Number of Residues12
DetailsBINDING SITE FOR RESIDUE HEM L 147
ChainResidue
LHIS92
LLEU96
LASN102
LLEU106
LHOH152
LTHR38
LPHE41
LPHE42
LHIS63
LLYS66
LVAL67
LSER70

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: distal binding residue
ChainResidueDetails
BHIS63
DHIS63
JHIS63
LHIS63

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: proximal binding residue
ChainResidueDetails
BHIS92
DHIS92
JHIS92
LHIS92

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PDB entries from 2024-07-17

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