Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2RGW

Catalytic Subunit of M. jannaschii Aspartate Transcarbamoylase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004070	molecular_function	aspartate carbamoyltransferase activity
A	0004088	molecular_function	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A	0005737	cellular_component	cytoplasm
A	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0006520	biological_process	amino acid metabolic process
A	0006541	biological_process	glutamine metabolic process
A	0016597	molecular_function	amino acid binding
A	0016740	molecular_function	transferase activity
A	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
A	0044205	biological_process	'de novo' UMP biosynthetic process
B	0004070	molecular_function	aspartate carbamoyltransferase activity
B	0004088	molecular_function	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B	0005737	cellular_component	cytoplasm
B	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0006520	biological_process	amino acid metabolic process
B	0006541	biological_process	glutamine metabolic process
B	0016597	molecular_function	amino acid binding
B	0016740	molecular_function	transferase activity
B	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
B	0044205	biological_process	'de novo' UMP biosynthetic process
C	0004070	molecular_function	aspartate carbamoyltransferase activity
C	0004088	molecular_function	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C	0005737	cellular_component	cytoplasm
C	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
C	0006221	biological_process	pyrimidine nucleotide biosynthetic process
C	0006520	biological_process	amino acid metabolic process
C	0006541	biological_process	glutamine metabolic process
C	0016597	molecular_function	amino acid binding
C	0016740	molecular_function	transferase activity
C	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
C	0044205	biological_process	'de novo' UMP biosynthetic process
D	0004070	molecular_function	aspartate carbamoyltransferase activity
D	0004088	molecular_function	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D	0005737	cellular_component	cytoplasm
D	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
D	0006221	biological_process	pyrimidine nucleotide biosynthetic process
D	0006520	biological_process	amino acid metabolic process
D	0006541	biological_process	glutamine metabolic process
D	0016597	molecular_function	amino acid binding
D	0016740	molecular_function	transferase activity
D	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
D	0044205	biological_process	'de novo' UMP biosynthetic process
E	0004070	molecular_function	aspartate carbamoyltransferase activity
E	0004088	molecular_function	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E	0005737	cellular_component	cytoplasm
E	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
E	0006221	biological_process	pyrimidine nucleotide biosynthetic process
E	0006520	biological_process	amino acid metabolic process
E	0006541	biological_process	glutamine metabolic process
E	0016597	molecular_function	amino acid binding
E	0016740	molecular_function	transferase activity
E	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
E	0044205	biological_process	'de novo' UMP biosynthetic process
F	0004070	molecular_function	aspartate carbamoyltransferase activity
F	0004088	molecular_function	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F	0005737	cellular_component	cytoplasm
F	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
F	0006221	biological_process	pyrimidine nucleotide biosynthetic process
F	0006520	biological_process	amino acid metabolic process
F	0006541	biological_process	glutamine metabolic process
F	0016597	molecular_function	amino acid binding
F	0016740	molecular_function	transferase activity
F	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
F	0044205	biological_process	'de novo' UMP biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 351

Chain	Residue
A	LYS63
A	HOH402
A	HOH403
A	HOH404
B	LYS63
B	HOH405
C	LYS63
C	HOH408

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 D 352

Chain	Residue
D	HOH479
D	HOH481
D	HOH482
E	LYS63
E	HOH482
F	LYS63
F	HOH485
D	LYS63

Functional Information from PROSITE/UniProt

site_id	PS00097
Number of Residues	8
Details	CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FyEpSTRT

Chain	Residue	Details
A	PHE47-THR54

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00001

Chain	Residue	Details
A	ARG53
A	PRO264
B	ARG53
B	THR54
B	LYS82
B	ARG103
B	HIS131
B	GLN134
B	ARG164
B	ARG226
B	LEU263
A	THR54
B	PRO264
C	ARG53
C	THR54
C	LYS82
C	ARG103
C	HIS131
C	GLN134
C	ARG164
C	ARG226
C	LEU263
A	LYS82
C	PRO264
D	ARG53
D	THR54
D	LYS82
D	ARG103
D	HIS131
D	GLN134
D	ARG164
D	ARG226
D	LEU263
A	ARG103
D	PRO264
E	ARG53
E	THR54
E	LYS82
E	ARG103
E	HIS131
E	GLN134
E	ARG164
E	ARG226
E	LEU263
A	HIS131
E	PRO264
F	ARG53
F	THR54
F	LYS82
F	ARG103
F	HIS131
F	GLN134
F	ARG164
F	ARG226
F	LEU263
A	GLN134
F	PRO264
A	ARG164
A	ARG226
A	LEU263

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1at1

Chain	Residue	Details
A	ARG103
A	THR54
A	HIS131
A	ARG53

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1at1

Chain	Residue	Details
B	ARG103
B	THR54
B	HIS131
B	ARG53

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1at1

Chain	Residue	Details
C	ARG103
C	THR54
C	HIS131
C	ARG53

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1at1

Chain	Residue	Details
D	ARG103
D	THR54
D	HIS131
D	ARG53

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1at1

Chain	Residue	Details
E	ARG103
E	THR54
E	HIS131
E	ARG53

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1at1

Chain	Residue	Details
F	ARG103
F	THR54
F	HIS131
F	ARG53

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)