2REO
Crystal structure of human sulfotransferase 1C3 (Sult1C3) in complex with PAP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004027 | molecular_function | alcohol sulfotransferase activity |
| A | 0004062 | molecular_function | aryl sulfotransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006790 | biological_process | sulfur compound metabolic process |
| A | 0006805 | biological_process | xenobiotic metabolic process |
| A | 0008146 | molecular_function | sulfotransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0050427 | biological_process | 3'-phosphoadenosine 5'-phosphosulfate metabolic process |
| A | 0050656 | molecular_function | 3'-phosphoadenosine 5'-phosphosulfate binding |
| A | 0051923 | biological_process | sulfation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE A3P A 401 |
| Chain | Residue |
| A | LYS56 |
| A | THR236 |
| A | PHE238 |
| A | MET241 |
| A | PHE264 |
| A | MET265 |
| A | ARG266 |
| A | LYS267 |
| A | GLY268 |
| A | SER57 |
| A | GLY58 |
| A | THR59 |
| A | THR60 |
| A | TRP61 |
| A | ARG139 |
| A | SER147 |
| A | TYR202 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q06520","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17425406","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of human sulfotransferase 1C3 (SULT1C3) in complex with PAP.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"2H8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2REO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
