2REO

Crystal structure of human sulfotransferase 1C3 (Sult1C3) in complex with PAP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004027	molecular_function	alcohol sulfotransferase activity
A	0004062	molecular_function	aryl sulfotransferase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0006790	biological_process	sulfur compound metabolic process
A	0006805	biological_process	xenobiotic metabolic process
A	0008146	molecular_function	sulfotransferase activity
A	0016740	molecular_function	transferase activity
A	0050427	biological_process	3'-phosphoadenosine 5'-phosphosulfate metabolic process
A	0050656	molecular_function	3'-phosphoadenosine 5'-phosphosulfate binding
A	0051923	biological_process	sulfation

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE A3P A 401

Chain	Residue
A	LYS56
A	THR236
A	PHE238
A	MET241
A	PHE264
A	MET265
A	ARG266
A	LYS267
A	GLY268
A	SER57
A	GLY58
A	THR59
A	THR60
A	TRP61
A	ARG139
A	SER147
A	TYR202

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:Q06520

Chain	Residue	Details
A	HIS117

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:17425406, ECO:0000269|Ref.7, ECO:0007744|PDB:2H8K, ECO:0007744|PDB:2REO

Chain	Residue	Details
A	LYS56
A	ARG139
A	SER147
A	TYR202
A	THR236
A	PHE264

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	LYS115

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