2RDB

X-ray Crystal Structure of Toluene/o-Xylene Monooxygenase Hydroxylase I100W Mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0004497	molecular_function	monooxygenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
C	0004497	molecular_function	monooxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GOL A 4975

Chain	Residue
A	TRP100
A	FE500
A	HOH5001
A	HOH5057
A	GLU104
A	ALA107
A	GLU134
A	PHE176
A	GLU197
A	THR201
A	GLU231
A	FE499

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 3287

Chain	Residue
A	HIS96
A	TRP100
A	GLN204
A	LEU272
A	THR273

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site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE P6G A 4974

Chain	Residue
A	GLU32
A	MET33
A	ARG37
A	THR182
A	ARG183
A	ASP184
A	ALA187
A	GLN256
A	ILE439
A	ASP440
A	HOH4987
A	HOH5016
A	HOH5054
B	PRO53
B	MET54

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 499

Chain	Residue
A	GLU104
A	GLU134
A	HIS137
A	FE500
A	GOL4975
A	HOH5001
A	HOH5057

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 500

Chain	Residue
A	GLU134
A	GLU197
A	GLU231
A	HIS234
A	FE499
A	GOL4975
A	HOH5057

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site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MPO B 4401

Chain	Residue
B	PHE63
B	LEU67
B	LYS68
B	HIS69
B	ASP70
B	ASP71
B	TRP72
B	ASN73
B	PRO147
B	TRP215

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