Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004198 | molecular_function | calcium-dependent cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 365 |
| Chain | Residue |
| A | GLY101 |
| A | ASP106 |
| A | GLU185 |
| A | HOH400 |
| A | HOH431 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 366 |
| Chain | Residue |
| A | GLU333 |
| A | HOH390 |
| A | GLU302 |
| A | ASP309 |
| A | MET329 |
| A | ASP331 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 663 |
| Chain | Residue |
| A | GLN96 |
| A | PHE97 |
| A | SER140 |
| A | PHE141 |
| A | GLN142 |
| A | HOH425 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 664 |
| Chain | Residue |
| A | GLN40 |
| A | LYS84 |
| A | HOH414 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 665 |
| Chain | Residue |
| A | ILE35 |
| A | LYS36 |
| A | SER65 |
| A | HOH381 |
| A | HOH507 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE K2Z A 367 |
| Chain | Residue |
| A | GLN109 |
| A | GLY110 |
| A | LEU112 |
| A | GLY113 |
| A | ASP114 |
| A | CYS115 |
| A | TRP116 |
| A | GLY207 |
| A | GLY208 |
| A | THR210 |
| A | GLY271 |
| A | HIS272 |
| A | TRP298 |
| A | HOH500 |
| A | HOH537 |
| A | HOH613 |
| A | HOH621 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 661 |
| Chain | Residue |
| A | LEU38 |
| A | ALA60 |
| A | ARG87 |
| A | GLU90 |
| A | LEU167 |
| A | HOH447 |
| A | HOH582 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 662 |
| Chain | Residue |
| A | LEU91 |
| A | GLY173 |
| A | LYS174 |
| A | GLU215 |
| A | GLY220 |
| A | THR222 |
| A | HOH415 |
| A | HOH473 |
| A | HOH609 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGaLGDCWLlAA |
| Chain | Residue | Details |
| A | GLN109-ALA120 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS115 | |
| A | HIS272 | |
| A | ASN296 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; for 75 kDa form => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY27 | |
| Chain | Residue | Details |
| A | THR354 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1kfu |
| Chain | Residue | Details |
| A | HIS272 | |
| A | GLN109 | |
| A | ASN296 | |
| A | CYS115 | |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1kfu |
| Chain | Residue | Details |
| A | HIS272 | |
| A | GLN109 | |
| A | TRP298 | |
| A | ASN296 | |
| A | CYS115 | |
