2R8U

Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000132	biological_process	establishment of mitotic spindle orientation
A	0000922	cellular_component	spindle pole
A	0001578	biological_process	microtubule bundle formation
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005794	cellular_component	Golgi apparatus
A	0005813	cellular_component	centrosome
A	0005815	cellular_component	microtubule organizing center
A	0005819	cellular_component	spindle
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005874	cellular_component	microtubule
A	0005881	cellular_component	cytoplasmic microtubule
A	0005925	cellular_component	focal adhesion
A	0008017	molecular_function	microtubule binding
A	0008104	biological_process	intracellular protein localization
A	0015630	cellular_component	microtubule cytoskeleton
A	0016477	biological_process	cell migration
A	0030981	cellular_component	cortical microtubule cytoskeleton
A	0031110	biological_process	regulation of microtubule polymerization or depolymerization
A	0031115	biological_process	negative regulation of microtubule polymerization
A	0031116	biological_process	positive regulation of microtubule polymerization
A	0031253	cellular_component	cell projection membrane
A	0035371	cellular_component	microtubule plus-end
A	0035372	biological_process	protein localization to microtubule
A	0036064	cellular_component	ciliary basal body
A	0042802	molecular_function	identical protein binding
A	0042995	cellular_component	cell projection
A	0045296	molecular_function	cadherin binding
A	0046785	biological_process	microtubule polymerization
A	0051010	molecular_function	microtubule plus-end binding
A	0051225	biological_process	spindle assembly
A	0051233	cellular_component	spindle midzone
A	0051301	biological_process	cell division
A	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
A	0097431	cellular_component	mitotic spindle pole
A	0120283	molecular_function	protein serine/threonine kinase binding
A	1902480	biological_process	protein localization to mitotic spindle
A	1902888	biological_process	protein localization to astral microtubule
A	1905721	cellular_component	mitotic spindle astral microtubule end
A	1990498	cellular_component	mitotic spindle microtubule
B	0000132	biological_process	establishment of mitotic spindle orientation
B	0000922	cellular_component	spindle pole
B	0001578	biological_process	microtubule bundle formation
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005794	cellular_component	Golgi apparatus
B	0005813	cellular_component	centrosome
B	0005815	cellular_component	microtubule organizing center
B	0005819	cellular_component	spindle
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0005874	cellular_component	microtubule
B	0005881	cellular_component	cytoplasmic microtubule
B	0005925	cellular_component	focal adhesion
B	0008017	molecular_function	microtubule binding
B	0008104	biological_process	intracellular protein localization
B	0015630	cellular_component	microtubule cytoskeleton
B	0016477	biological_process	cell migration
B	0030981	cellular_component	cortical microtubule cytoskeleton
B	0031110	biological_process	regulation of microtubule polymerization or depolymerization
B	0031115	biological_process	negative regulation of microtubule polymerization
B	0031116	biological_process	positive regulation of microtubule polymerization
B	0031253	cellular_component	cell projection membrane
B	0035371	cellular_component	microtubule plus-end
B	0035372	biological_process	protein localization to microtubule
B	0036064	cellular_component	ciliary basal body
B	0042802	molecular_function	identical protein binding
B	0042995	cellular_component	cell projection
B	0045296	molecular_function	cadherin binding
B	0046785	biological_process	microtubule polymerization
B	0051010	molecular_function	microtubule plus-end binding
B	0051225	biological_process	spindle assembly
B	0051233	cellular_component	spindle midzone
B	0051301	biological_process	cell division
B	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
B	0097431	cellular_component	mitotic spindle pole
B	0120283	molecular_function	protein serine/threonine kinase binding
B	1902480	biological_process	protein localization to mitotic spindle
B	1902888	biological_process	protein localization to astral microtubule
B	1905721	cellular_component	mitotic spindle astral microtubule end
B	1990498	cellular_component	mitotic spindle microtubule

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MOO A 269

Chain	Residue
A	SER16
A	ARG17
B	LYS34
B	GLU36
B	HOH270

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	204
Details	Domain: {"description":"Calponin-homology (CH)","evidences":[{"source":"PROSITE-ProRule","id":"PRU00044","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUL-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Potts A.","Barblan J.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-crotonyllysine","evidences":[{"source":"PubMed","id":"34608293","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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