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2R8U

Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0000132biological_processestablishment of mitotic spindle orientation
A0000922cellular_componentspindle pole
A0001578biological_processmicrotubule bundle formation
A0003723molecular_functionRNA binding
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005794cellular_componentGolgi apparatus
A0005813cellular_componentcentrosome
A0005815cellular_componentmicrotubule organizing center
A0005819cellular_componentspindle
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005874cellular_componentmicrotubule
A0005881cellular_componentcytoplasmic microtubule
A0005925cellular_componentfocal adhesion
A0007049biological_processcell cycle
A0008017molecular_functionmicrotubule binding
A0008104biological_processprotein localization
A0015630cellular_componentmicrotubule cytoskeleton
A0016477biological_processcell migration
A0019901molecular_functionprotein kinase binding
A0030981cellular_componentcortical microtubule cytoskeleton
A0031110biological_processregulation of microtubule polymerization or depolymerization
A0031115biological_processnegative regulation of microtubule polymerization
A0031116biological_processpositive regulation of microtubule polymerization
A0031253cellular_componentcell projection membrane
A0035371cellular_componentmicrotubule plus-end
A0035372biological_processprotein localization to microtubule
A0036064cellular_componentciliary basal body
A0042802molecular_functionidentical protein binding
A0042995cellular_componentcell projection
A0045296molecular_functioncadherin binding
A0046785biological_processmicrotubule polymerization
A0051010molecular_functionmicrotubule plus-end binding
A0051225biological_processspindle assembly
A0051233cellular_componentspindle midzone
A0051301biological_processcell division
A0051315biological_processattachment of mitotic spindle microtubules to kinetochore
A0071539biological_processprotein localization to centrosome
A0097431cellular_componentmitotic spindle pole
A1902888biological_processprotein localization to astral microtubule
A1905515biological_processnon-motile cilium assembly
A1905721cellular_componentmitotic spindle astral microtubule end
B0000132biological_processestablishment of mitotic spindle orientation
B0000922cellular_componentspindle pole
B0001578biological_processmicrotubule bundle formation
B0003723molecular_functionRNA binding
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005794cellular_componentGolgi apparatus
B0005813cellular_componentcentrosome
B0005815cellular_componentmicrotubule organizing center
B0005819cellular_componentspindle
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005874cellular_componentmicrotubule
B0005881cellular_componentcytoplasmic microtubule
B0005925cellular_componentfocal adhesion
B0007049biological_processcell cycle
B0008017molecular_functionmicrotubule binding
B0008104biological_processprotein localization
B0015630cellular_componentmicrotubule cytoskeleton
B0016477biological_processcell migration
B0019901molecular_functionprotein kinase binding
B0030981cellular_componentcortical microtubule cytoskeleton
B0031110biological_processregulation of microtubule polymerization or depolymerization
B0031115biological_processnegative regulation of microtubule polymerization
B0031116biological_processpositive regulation of microtubule polymerization
B0031253cellular_componentcell projection membrane
B0035371cellular_componentmicrotubule plus-end
B0035372biological_processprotein localization to microtubule
B0036064cellular_componentciliary basal body
B0042802molecular_functionidentical protein binding
B0042995cellular_componentcell projection
B0045296molecular_functioncadherin binding
B0046785biological_processmicrotubule polymerization
B0051010molecular_functionmicrotubule plus-end binding
B0051225biological_processspindle assembly
B0051233cellular_componentspindle midzone
B0051301biological_processcell division
B0051315biological_processattachment of mitotic spindle microtubules to kinetochore
B0071539biological_processprotein localization to centrosome
B0097431cellular_componentmitotic spindle pole
B1902888biological_processprotein localization to astral microtubule
B1905515biological_processnon-motile cilium assembly
B1905721cellular_componentmitotic spindle astral microtubule end
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MOO A 269
ChainResidue
ASER16
AARG17
BLYS34
BGLU36
BHOH270

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylalanine => ECO:0000269|Ref.6, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378
ChainResidueDetails
AALA2
BALA2

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N6-crotonyllysine => ECO:0000269|PubMed:34608293
ChainResidueDetails
ALYS66
BLYS66

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15592455
ChainResidueDetails
ATYR124
BTYR124

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER155
ASER165
BSER155
BSER165

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000269|PubMed:23001180
ChainResidueDetails
ALYS220
BLYS220

218853

PDB entries from 2024-04-24

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