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2R6D

Crystal Form B1

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003678molecular_functionDNA helicase activity
A0004386molecular_functionhelicase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005829cellular_componentcytosol
A0006260biological_processDNA replication
A0006268biological_processDNA unwinding involved in DNA replication
A0006269biological_processDNA replication, synthesis of primer
A0016787molecular_functionhydrolase activity
A0016853molecular_functionisomerase activity
A0016887molecular_functionATP hydrolysis activity
A0042802molecular_functionidentical protein binding
A1990077cellular_componentprimosome complex
B0003677molecular_functionDNA binding
B0003678molecular_functionDNA helicase activity
B0004386molecular_functionhelicase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005829cellular_componentcytosol
B0006260biological_processDNA replication
B0006268biological_processDNA unwinding involved in DNA replication
B0006269biological_processDNA replication, synthesis of primer
B0016787molecular_functionhydrolase activity
B0016853molecular_functionisomerase activity
B0016887molecular_functionATP hydrolysis activity
B0042802molecular_functionidentical protein binding
B1990077cellular_componentprimosome complex
C0003677molecular_functionDNA binding
C0003678molecular_functionDNA helicase activity
C0004386molecular_functionhelicase activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005829cellular_componentcytosol
C0006260biological_processDNA replication
C0006268biological_processDNA unwinding involved in DNA replication
C0006269biological_processDNA replication, synthesis of primer
C0016787molecular_functionhydrolase activity
C0016853molecular_functionisomerase activity
C0016887molecular_functionATP hydrolysis activity
C0042802molecular_functionidentical protein binding
C1990077cellular_componentprimosome complex
D0003677molecular_functionDNA binding
D0003678molecular_functionDNA helicase activity
D0004386molecular_functionhelicase activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005829cellular_componentcytosol
D0006260biological_processDNA replication
D0006268biological_processDNA unwinding involved in DNA replication
D0006269biological_processDNA replication, synthesis of primer
D0016787molecular_functionhydrolase activity
D0016853molecular_functionisomerase activity
D0016887molecular_functionATP hydrolysis activity
D0042802molecular_functionidentical protein binding
D1990077cellular_componentprimosome complex
E0003677molecular_functionDNA binding
E0003678molecular_functionDNA helicase activity
E0004386molecular_functionhelicase activity
E0005515molecular_functionprotein binding
E0005524molecular_functionATP binding
E0005829cellular_componentcytosol
E0006260biological_processDNA replication
E0006268biological_processDNA unwinding involved in DNA replication
E0006269biological_processDNA replication, synthesis of primer
E0016787molecular_functionhydrolase activity
E0016853molecular_functionisomerase activity
E0016887molecular_functionATP hydrolysis activity
E0042802molecular_functionidentical protein binding
E1990077cellular_componentprimosome complex
F0003677molecular_functionDNA binding
F0003678molecular_functionDNA helicase activity
F0004386molecular_functionhelicase activity
F0005515molecular_functionprotein binding
F0005524molecular_functionATP binding
F0005829cellular_componentcytosol
F0006260biological_processDNA replication
F0006268biological_processDNA unwinding involved in DNA replication
F0006269biological_processDNA replication, synthesis of primer
F0016787molecular_functionhydrolase activity
F0016853molecular_functionisomerase activity
F0016887molecular_functionATP hydrolysis activity
F0042802molecular_functionidentical protein binding
F1990077cellular_componentprimosome complex
Functional Information from PROSITE/UniProt
site_idPS00039
Number of Residues9
DetailsDEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. LLDEADRkI
ChainResidueDetails
ALEU139-ILE147

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsACT_SITE: Nucleophile => ECO:0000305|PubMed:12235389, ECO:0000305|PubMed:23022319
ChainResidueDetails
AGLU241
BGLU241
CGLU241
DGLU241
EGLU241
FGLU241

site_idSWS_FT_FI2
Number of Residues54
DetailsBINDING: BINDING => ECO:0000305|PubMed:23022319, ECO:0007744|PDB:4ESV
ChainResidueDetails
ASER213
BSER213
BGLY215
BLYS216
BTHR217
BALA218
BARG250
BLYS418
BGLN419
BARG420
CSER213
AGLY215
CGLY215
CLYS216
CTHR217
CALA218
CARG250
CLYS418
CGLN419
CARG420
DSER213
DGLY215
ALYS216
DLYS216
DTHR217
DALA218
DARG250
DLYS418
DGLN419
DARG420
ESER213
EGLY215
ELYS216
ATHR217
ETHR217
EALA218
EARG250
ELYS418
EGLN419
EARG420
FSER213
FGLY215
FLYS216
FTHR217
AALA218
FALA218
FARG250
FLYS418
FGLN419
FARG420
AARG250
ALYS418
AGLN419
AARG420

site_idSWS_FT_FI3
Number of Residues6
DetailsBINDING: BINDING => ECO:0000305|PubMed:23022319
ChainResidueDetails
AGLN362
BGLN362
CGLN362
DGLN362
EGLN362
FGLN362

site_idSWS_FT_FI4
Number of Residues18
DetailsBINDING: BINDING => ECO:0000269|PubMed:23022319, ECO:0007744|PDB:4ESV
ChainResidueDetails
AARG381
DARG381
DGLU382
DGLY384
EARG381
EGLU382
EGLY384
FARG381
FGLU382
FGLY384
AGLU382
AGLY384
BARG381
BGLU382
BGLY384
CARG381
CGLU382
CGLY384

site_idSWS_FT_FI5
Number of Residues6
DetailsSITE: Gamma-phosphate sensor => ECO:0000305|PubMed:12235389
ChainResidueDetails
AGLN362
BGLN362
CGLN362
DGLN362
EGLN362
FGLN362

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PDB entries from 2024-08-28

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