2QZW
Secreted aspartic proteinase (Sap) 1 from Candida albicans
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0009277 | cellular_component | fungal-type cell wall |
| A | 0016485 | biological_process | protein processing |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030163 | biological_process | protein catabolic process |
| A | 0031505 | biological_process | fungal-type cell wall organization |
| A | 0035756 | biological_process | symbiont-mediated migration across host transepithelium |
| A | 0044406 | biological_process | adhesion of symbiont to host |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052553 | biological_process | symbiont-mediated perturbation of host immune response |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0009277 | cellular_component | fungal-type cell wall |
| B | 0016485 | biological_process | protein processing |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0030163 | biological_process | protein catabolic process |
| B | 0031505 | biological_process | fungal-type cell wall organization |
| B | 0035756 | biological_process | symbiont-mediated migration across host transepithelium |
| B | 0044406 | biological_process | adhesion of symbiont to host |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052553 | biological_process | symbiont-mediated perturbation of host immune response |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VIVDTGSSDLWV |
| Chain | Residue | Details |
| A | VAL29-VAL40 | |
| A | VAL215-LEU226 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 626 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P0CY29","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR221 | |
| A | SER35 | |
| A | ASP218 | |
| A | ASP32 |
| site_id | CSA10 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | THR221 | |
| B | ASP218 | |
| B | ASP32 | |
| B | THR33 |
| site_id | CSA11 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP32 |
| site_id | CSA12 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP32 |
| site_id | CSA13 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP218 |
| site_id | CSA14 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP218 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | THR221 | |
| B | SER35 | |
| B | ASP218 | |
| B | ASP32 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP218 | |
| A | ASP32 | |
| A | THR33 | |
| A | SER219 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP218 | |
| B | ASP32 | |
| B | THR33 | |
| B | SER219 |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER35 | |
| A | ASP218 | |
| A | ASP32 |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | SER35 | |
| B | ASP218 | |
| B | ASP32 |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER35 | |
| A | TYR84 | |
| A | ASP218 | |
| A | ASP32 |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | SER35 | |
| B | TYR84 | |
| B | ASP218 | |
| B | ASP32 |
| site_id | CSA9 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR221 | |
| A | ASP218 | |
| A | ASP32 | |
| A | THR33 |
